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Usp48 Gene Detail
Summary
  • Symbol
    Usp48
  • Name
    ubiquitin specific peptidase 48
  • Synonyms
    2810449C13Rik, D330022K21Rik, MGC:25724, Usp31
  • Feature Type
    protein coding gene
  • IDs
    MGI:2158502
    NCBI Gene: 170707
  • Gene Overview
    MyGene.info: USP48
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:137594149-137658537 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 70.00 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    817 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2158502
protein coding gene Chr4:137593755-137658537 (.)
129S1/SvImJ MGP_129S1SvImJ_G0028985
protein coding gene Chr4:140247612-140314717 (+)
A/J MGP_AJ_G0028944
protein coding gene Chr4:134277406-134343192 (+)
AKR/J MGP_AKRJ_G0028896
protein coding gene Chr4:138130227-138195991 (+)
BALB/cJ MGP_BALBcJ_G0028968
protein coding gene Chr4:134957636-135025237 (+)
C3H/HeJ MGP_C3HHeJ_G0028682
protein coding gene Chr4:138471104-138542616 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029409
protein coding gene Chr4:145245520-145316036 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026680
protein coding gene Chr4:127283186-127348335 (+)
CAST/EiJ MGP_CASTEiJ_G0028114
protein coding gene Chr4:136605630-136675761 (+)
CBA/J MGP_CBAJ_G0028647
protein coding gene Chr4:149349773-149429482 (+)
DBA/2J MGP_DBA2J_G0028796
protein coding gene Chr4:134672767-134738602 (+)
FVB/NJ MGP_FVBNJ_G0028763
protein coding gene Chr4:133667125-133733873 (+)
LP/J MGP_LPJ_G0028895
protein coding gene Chr4:140332914-140402219 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028789
protein coding gene Chr4:153369380-153437728 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029447
protein coding gene Chr4:138606921-138673202 (+)
PWK/PhJ MGP_PWKPhJ_G0027834
protein coding gene Chr4:131496163-131563358 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027660
protein coding gene Chr4:134385316-134458012 (+)
WSB/EiJ MGP_WSBEiJ_G0028192
protein coding gene Chr4:138820729-138891568 (+)



Homology
more
  • Human Ortholog
    USP48, ubiquitin specific peptidase 48
  • Vertebrate Orthologs
    10
  • Human Ortholog
    USP48, ubiquitin specific peptidase 48
    Orthology source: HomoloGene, HGNC
  • Synonyms
    RAP1GA1, USP31
  • Links
    NCBI Gene ID: 84196
    neXtProt AC: NX_Q86UV5
    UniProt: Q86UV5

  • Chr Location
    1p36.12; chr1:21678298-21783620 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 12988
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: USP48
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 170707 NCBI Gene Model | MGI Sequence Detail 64389 C57BL/6J ±  kb
transcript NM_130879 RefSeq | MGI Sequence Detail 5783 C57BL/6  
polypeptide Q3V0C5 UniProt | EBI | MGI Sequence Detail 1052 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 186
    cDNA 184
    Primer pair 1
    Other 1

    Microarray probesets 7
Other
Accession IDs
less
MGI:1920015, MGI:2140189, MGI:2445055
References
more
  • Summaries
    All 43
    Gene Ontology 7
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:239017 Steinmetz CC, et al., Upregulation of mu3A Drives Homeostatic Plasticity by Rerouting AMPAR into the Recycling Endosomal Pathway. Cell Rep. 2016 Sep 06;16(10):2711-22

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory