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Ahsp
Gene Detail
Symbol

Name
ID
Ahsp
alpha hemoglobin stabilizing protein
MGI:2158492
Synonyms
Eraf
Feature Type
protein coding gene
Genetic Map
Chromosome Unknown
Vertebrate
homology
HCOP human homology predictions: AHSP
Human
homologs
AHSP, alpha hemoglobin stabilizing protein
Orthology source: HGNC

IDs:
NCBI Gene ID: 51327
neXtProt AC: NX_Q9NZD4

Human Synonyms: EDRF, ERAF

Human Chr (Location): 16p11.2; chr16:31527852-31528803 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
 
Mice homozygous for a targeted mutation are viable and developmentally normal but exhibit reticulocytosis and abnormal erythrocyte morphology with intracellular inclusion bodies that stain positively for denatured hemoglobins.
 
Mutations Annotated to Human Diseases (2)   
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process erythrocyte differentiation, hemoglobin metabolic process, ...
Component cytoplasm
Function hemoglobin binding
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (46)    Tissues (2)    Images (23)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 46
cDNA source data(43)
Other mouse links: Allen Institute   GEO  
Molecular
reagents
All nucleic(43) cDNA(43)
Microarray probesets(1)
Other database
links
Entrez Gene 170812
UniGene 423023
DoTS DT.101350150
Sequences
Representative SequencesLengthStrain/SpeciesFlank
transcript NM_133245 RefSeq | MGI Sequence Detail 494 C57BL/6 
polypeptide Q9CY02 UniProt | EBI | MGI Sequence Detail 102 Not Applicable 

For the selected sequences
All sequences(11) RefSeq(2) UniProt(2)
Protein-related
information
ResourceIDDescription
InterPro IPR015317 Alpha-haemoglobin stabilising protein
Protein Ontology PR:000003863 alpha-hemoglobin-stabilizing protein
Graphical View of Protein Domain Structure
References
(Earliest) J:73795 Miele G, et al., A novel erythroid-specific marker of transmissible spongiform encephalopathies. Nat Med. 2001 Mar;7(3):361-4
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(23)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory