About   Help   FAQ
Hdac10 Gene Detail
Summary
  • Symbol
    Hdac10
  • Name
    histone deacetylase 10
  • Feature Type
    protein coding gene
  • IDs
    MGI:2158340
    NCBI Gene: 170787
  • Gene Overview
    MyGene.info: HDAC10
Location & Maps
more
  • Sequence Map
    Chr15:89123307-89128700 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5394 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 44.64 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    HDAC10, histone deacetylase 10
  • Vertebrate Orthologs
    10
  • Human Ortholog
    HDAC10, histone deacetylase 10
    Orthology source: HGNC, HomoloGene
  • Synonyms
    HD10
  • Links
    NCBI Gene ID: 83933
    neXtProt AC: NX_Q969S8

  • Chr Location
    22q13.31; chr22:50245183-50251405 (-)  GRCh38.p2

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    22 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Radiation induced
    2
  • Targeted
    3
  • Genomic Mutations
    3 involving Hdac10
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017283 VEGA Gene Model | MGI Sequence Detail 5394 C57BL/6J ±  kb
transcript OTTMUST00000041885 VEGA | MGI Sequence Detail 2412 Not Applicable  
polypeptide OTTMUSP00000018838 VEGA | MGI Sequence Detail 666 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    7 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 47
    cDNA 46
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:2146231
References
more
  • Summaries
    All 32
    Developmental Gene Expression 5
    Diseases 1
    Gene Ontology 4
    Phenotypes 22
  • Earliest
    J:73643 Kao HY, et al., Isolation and characterization of mammalian HDAC10, a novel histone deacetylase. J Biol Chem. 2002 Jan 4;277(1):187-93
  • Latest
    J:213843 Tiwari S, et al., Histone deacetylase expression patterns in developing murine optic nerve. BMC Dev Biol. 2014;14:30

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/22/2016
MGI 6.04
The Jackson Laboratory