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Hdac10 Gene Detail
Summary
  • Symbol
    Hdac10
  • Name
    histone deacetylase 10
  • Feature Type
    protein coding gene
  • IDs
    MGI:2158340
    NCBI Gene: 170787
  • Gene Overview
    MyGene.info: HDAC10
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr15:89123307-89128700 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5394 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 44.64 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    HDAC10, histone deacetylase 10
  • Vertebrate Orthologs
    10
  • Human Ortholog
    HDAC10, histone deacetylase 10
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HD10
  • Links
    NCBI Gene ID: 83933
    neXtProt AC: NX_Q969S8
    UniProt: Q969S8

  • Chr Location
    22q13.33; chr22:50245183-50251405 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 23749
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: HDAC10
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    24 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000017283 VEGA Gene Model | MGI Sequence Detail 5394 C57BL/6J ±  kb
    transcript OTTMUST00000041885 VEGA | MGI Sequence Detail 2412 Not Applicable  
    polypeptide OTTMUSP00000018838 VEGA | MGI Sequence Detail 666 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      7 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 48
      cDNA 47
      Primer pair 1

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2146231
    References
    more
    • Summaries
      All 54
      Developmental Gene Expression 6
      Diseases 1
      Gene Ontology 4
      Phenotypes 24
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:240709 Ferreira RC, et al., Histone Deacetylase 1 Is Essential for Rod Photoreceptor Differentiation by Regulating Acetylation at Histone H3 Lysine 9 and Histone H4 Lysine 12 in the Mouse Retina. J Biol Chem. 2017 Feb 10;292(6):2422-2440

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    07/31/2018
    MGI 6.12
    The Jackson Laboratory