Cd209d
Gene Detail

Symbol Name ID

Cd209d CD209d antigen MGI:2157947

Synonyms

mSIGNR3, SIGNR3, SIGN-R3

Feature Type

protein coding gene

Genetic Map

Chromosome 8

1.92 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr8:3871824-3878499 bp, - strand From NCBI annotation of GRCm38   6676 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:8603  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee

Gene Tree: Cd209d

Human homologs

Human Homolog		CLEC4M, C-type lectin domain family 4, member M
NCBI Gene ID		10332
neXtProt AC		NX_Q9H2X3
Human Synonyms		CD209L, CD299, DC-SIGN2, DCSIGNR, DC-SIGNR, HP10347, LSIGN, L-SIGN
Human Chr (Location)		19p13; chr19:7828035-7834491 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(5) : Targeted(5)
 

Mice homozygous for a knock-out allele exhibit normal susceptibility to bacterial infection.

 

Gene Ontology (GO) classifications

All GO classifications: (10 annotations)

Process	defense response to bacterium, endocytosis, ...
Component	integral to membrane, membrane
Function	carbohydrate binding, mannose binding, ...

External Resources: FuncBase

Expression

cDNA source data(6)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(8) Genomic(1) cDNA(6) Other(1)
Microarray probesets(2)

Other database links

Ensembl Gene Model	ENSMUSG00000031495 (Evidence)
Entrez Gene	170779 (Evidence)
UniGene	111026
DFCI	TC1588376
DoTS	DT.485085, DT.97406774
NIA Mouse Gene Index	U029546
Consensus CDS Project	CCDS22075.1
International Mouse Knockout Project Status	Cd209d

Sequences

Length	Strain/Species
genomic	170779	NCBI Gene Model | MGI Sequence Detail	6676	C57BL/6J
transcript	NM_130904	RefSeq | MGI Sequence Detail	880	C57BL/6
polypeptide	Q91ZW8	UniProt | EBI | MGI Sequence Detail	237	Not Applicable

All sequences(21) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(28 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001304	C-type lectin
InterPro	IPR018378	C-type lectin, conserved site
InterPro	IPR016187	C-type lectin fold
InterPro	IPR016186	C-type lectin-like
Protein Ontology	PR:000006174	CD209 molecule-like protein D

Graphical View of Protein Domain Structure

References

(Earliest) J:72165 Park CG, et al., Five mouse homologues of the human dendritic cell C-type lectin, DC-SIGN. Int Immunol. 2001 Oct;13(10):1283-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(29)