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Cd209a
Gene Detail
Symbol

Name
ID
Cd209a
CD209a antigen
MGI:2157942
Synonyms
CD209, CIRE, Dcsign, DC-SIGN, DC-SIGN1, SIGNR5
Feature Type
protein coding gene
Genetic Map
Chromosome 8
1.92 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr8:3743395-3748984 bp, - strand
From NCBI annotation of GRCm38

  5590 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:129771  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 zebrafish

HCOP human homology predictions: CLEC4M
Gene Tree: Cd209a

Human
homologs
CLEC4M, C-type lectin domain family 4, member M
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 10332
neXtProt AC: NX_Q9H2X3

Human Synonyms: CD209L, CD299, DC-SIGN2, DCSIGNR, DC-SIGNR, HP10347, LSIGN, L-SIGN

Human Chr (Location): 19p13; chr19:7763054-7770558 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit normal susceptibility to bacterial infection despite altered lymphocyte numbers and increased inflammatory response..
 
Interactions
Cd209a interacts with 136 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process endocytosis, regulation of blood coagulation, ...
Component cell surface, integral component of membrane, ...
Function calcium-dependent protein binding, carbohydrate binding, ...
External Resources: FuncBase
Expression
cDNA source data(5)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: ZFIN cd209    NEW 
Molecular
reagents
All nucleic(7) Genomic(2) cDNA(5)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000031494 (Evidence)
Entrez Gene 170786 (Evidence)
UniGene 32510
DFCI TC1584413
DoTS DT.97342134, DT.110868907
NIA Mouse Gene Index U029543
Consensus CDS Project CCDS22073.1
International Mouse Phenotyping Consortium Status Cd209a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 170786 NCBI Gene Model | MGI Sequence Detail 5590 C57BL/6J ±  kb
transcript NM_133238 RefSeq | MGI Sequence Detail 1484 Not Specified 
polypeptide Q91ZX1 UniProt | EBI | MGI Sequence Detail 238 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(61 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001304 C-type lectin
InterPro IPR018378 C-type lectin, conserved site
InterPro IPR016187 C-type lectin fold
InterPro IPR016186 C-type lectin-like
Protein Ontology PR:000001301 CD209 molecule-like protein A
Graphical View of Protein Domain Structure
References
(Earliest) J:20938 Katz LC, Somatosensory development. A new level of refinement. Curr Biol. 1994 Sep 1;4(9):831-4
(Latest) J:217719 Orr SL, et al., A phenotype survey of 36 mutant mouse strains with gene-targeted defects in glycosyltransferases or glycan-binding proteins. Glycobiology. 2013 Mar;23(3):363-80
All references(36)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory