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Cd209a
Gene Detail
 Symbol
Name
ID
Cd209a
CD209a antigen
MGI:2157942
Synonyms CD209, CIRE, Dcsign, DC-SIGN, DC-SIGN1, SIGNR5
Feature Type protein coding gene
Genetic Map
Chromosome 8
1.92 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr8:3743395-3748984 bp, - strand
From NCBI annotation of GRCm38

  5590 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:129771  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 zebrafish

Gene Tree: Cd209a

Human
homologs
Human Homolog CLEC4M, C-type lectin domain family 4, member M
NCBI Gene ID 10332
neXtProt AC  NX_Q9H2X3
Human Synonyms  CD209L, CD299, DC-SIGN2, DCSIGNR, DC-SIGNR, HP10347, LSIGN, L-SIGN
Human Chr (Location)  19p13; chr19:7763133-7769605 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit normal susceptibility to bacterial infection.
 
Interactions
Cd209a interacts with 137 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process endocytosis, regulation of blood coagulation, ...
Component cell surface, integral component of membrane, ...
Function carbohydrate binding, mannose binding, ...
External Resources: FuncBase
Expression
cDNA source data(5)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(7) Genomic(2) cDNA(5)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000031494 (Evidence)
Entrez Gene170786 (Evidence)
UniGene32510
DFCITC1584413
DoTSDT.110868907, DT.97342134
NIA Mouse Gene IndexU029543
Consensus CDS ProjectCCDS22073.1
International Mouse Knockout Project StatusCd209a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 170786 NCBI Gene Model | MGI Sequence Detail 5590 C57BL/6J ±  kb
transcript NM_133238 RefSeq | MGI Sequence Detail 1484 Not Specified 
polypeptide Q91ZX1 UniProt | EBI | MGI Sequence Detail 238 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(61 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001304 C-type lectin
InterPro IPR018378 C-type lectin, conserved site
InterPro IPR016187 C-type lectin fold
InterPro IPR016186 C-type lectin-like
Protein Ontology PR:000001301 CD209 molecule-like protein A
Graphical View of Protein Domain Structure
References (Earliest) J:72165 Park CG, et al., Five mouse homologues of the human dendritic cell C-type lectin, DC-SIGN. Int Immunol. 2001 Oct;13(10):1283-90
(Latest) J:194602 Lu XJ, et al., LECT2 protects mice against bacterial sepsis by activating macrophages via the CD209a receptor. J Exp Med. 2013 Jan 14;210(1):5-13
All references(35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory