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Cdhr1
Gene Detail
Symbol

Name
ID
Cdhr1
cadherin-related family member 1
MGI:2157782
Synonyms
Pcdh21, Prcad
Feature Type
protein coding gene
Genetic Map
Chromosome 14
21.29 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr14:37077850-37098311 bp, - strand
From Ensembl annotation of GRCm38

  20462 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:13215  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CDHR1
Gene Tree: Cdhr1

Human
homologs
CDHR1, cadherin-related family member 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 92211
neXtProt AC: NX_Q96JP9

Human Synonyms: CORD15, PCDH21, PRCAD, RP65

Human Chr (Location): 10q23.1; chr10:84194635-84219621 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human CDHR1

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a targeted null mutation exhibit progressive degeneration of retinal photoreceptor cells and a slight reduction in light responses.
 
Interactions
Cdhr1 interacts with 264 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process cell adhesion, cellular process, ...
Component integral component of membrane, integral component of plasma membrane, ...
Function calcium ion binding, protein binding
External Resources: FuncBase
Expression
Literature Summary: (12 records)
Data Summary: Results (180)    Tissues (62)    Images (67)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 173
RT-PCR 7
cDNA source data(70)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: GEISHA CDHR1    NEW 
Molecular
reagents
All nucleic(74) cDNA(71) Primer pair(3)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000021803 (Evidence)
Entrez Gene 170677 (Evidence)
UniGene 156506
DFCI TC1578845
DoTS DT.60100248
NIA Mouse Gene Index U035424
Consensus CDS Project CCDS26952.1
International Mouse Phenotyping Consortium Status Cdhr1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021803 Ensembl Gene Model | MGI Sequence Detail 20462 C57BL/6J ±  kb
transcript ENSMUST00000022337 Ensembl | MGI Sequence Detail 4303 Not Applicable 
polypeptide ENSMUSP00000022337 Ensembl | MGI Sequence Detail 859 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(294 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002126 Cadherin
InterPro IPR020894 Cadherin conserved site
InterPro IPR015919 Cadherin-like
Protein Ontology PR:000012351 cadherin-related family member 1
References
(Earliest) J:73286 Rattner A, et al., A photoreceptor-specific cadherin is essential for the structural integrity of the outer segment and for photoreceptor survival. Neuron. 2001 Dec 6;32(5):775-86
(Latest) J:185648 Mizuguchi R, et al., Tbr2 deficiency in mitral and tufted cells disrupts excitatory-inhibitory balance of neural circuitry in the mouse olfactory bulb. J Neurosci. 2012 Jun 27;32(26):8831-44
All references(39)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory