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Cdhr1
Gene Detail
 Symbol
Name
ID
Cdhr1
cadherin-related family member 1
MGI:2157782
Synonyms Pcdh21, Prcad
Feature Type protein coding gene
Genetic Map
Chromosome 14
21.29 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr14:37077850-37098311 bp, - strand
From Ensembl annotation of GRCm38

  20462 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:13215  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Cdhr1

Human
homologs
Human Homolog CDHR1, cadherin-related family member 1
NCBI Gene ID 92211
neXtProt AC  NX_Q96JP9
Human Synonyms  CORD15, PCDH21, PRCAD, RP65
Human Chr (Location)  10q23.1; chr10:84194635-84219621 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human CDHR1
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a targeted null mutation exhibit progressive degeneration of retinal photoreceptor cells and a slight reduction in light responses.
 
Interactions
Cdhr1 interacts with 265 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process cell adhesion, cellular process, ...
Component integral component of membrane, integral component of plasma membrane, ...
Function calcium ion binding, protein binding
External Resources: FuncBase
Expression
Literature Summary: (12 records)
Data Summary: Results (168)    Tissues (51)    Images (62)
Theiler Stages: 20, 22, 23, 24, 26, 27, 28
Assay TypeResults
RNA in situ 168
cDNA source data(69)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(71) cDNA(70) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000021803 (Evidence)
Entrez Gene170677 (Evidence)
UniGene156506
DFCITC1578845
DoTSDT.60100248
NIA Mouse Gene IndexU035424
Consensus CDS ProjectCCDS26952.1
International Mouse Knockout Project StatusCdhr1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021803 Ensembl Gene Model | MGI Sequence Detail 20462 C57BL/6J ±  kb
transcript ENSMUST00000022337 Ensembl | MGI Sequence Detail 4303 Not Applicable 
polypeptide ENSMUSP00000022337 Ensembl | MGI Sequence Detail 859 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(294 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002126 Cadherin
InterPro IPR020894 Cadherin conserved site
InterPro IPR015919 Cadherin-like
Protein Ontology PR:000012351 cadherin-related family member 1
References (Earliest) J:73286 Rattner A, et al., A photoreceptor-specific cadherin is essential for the structural integrity of the outer segment and for photoreceptor survival. Neuron. 2001 Dec 6;32(5):775-86
(Latest) J:185648 Mizuguchi R, et al., Tbr2 deficiency in mitral and tufted cells disrupts excitatory-inhibitory balance of neural circuitry in the mouse olfactory bulb. J Neurosci. 2012 Jun 27;32(26):8831-44
All references(41)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory