Cdhr1
Gene Detail

Symbol Name ID

Cdhr1 cadherin-related family member 1 MGI:2157782

Synonyms

Pcdh21, Prcad

Feature Type

protein coding gene

Genetic Map

Chromosome 14

21.29 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr14:37077850-37098311 bp, - strand From Ensembl annotation of GRCm38   20462 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:13215  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Cdhr1

Human homologs

Human Homolog		CDHR1, cadherin-related family member 1
NCBI Gene ID		92211
neXtProt AC		NX_Q96JP9
Human Synonyms		CORD15, PCDH21, PRCAD, RP65
Human Chr (Location)		10q23.1; chr10:85954412-85979377 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human CDHR1

Alleles and phenotypes

All alleles(3) : Targeted(3)
 

Mice homozygous for a targeted null mutation exhibit progressive degeneration of retinal photoreceptor cells and a slight reduction in light responses.

 

Gene Ontology (GO) classifications

All GO classifications: (14 annotations)

Process	cell adhesion, cellular process, ...
Component	integral to membrane, integral to plasma membrane, ...
Function	calcium ion binding, protein binding

External Resources: FuncBase

Expression

Literature Summary: (12 records)
Data Summary: Results (168)    Tissues (50)    Images (62)
Theiler Stages: 20, 22, 23, 24, 26, 28

Assay Type	Results
RNA in situ	168

cDNA source data(69)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress

Molecular reagents

All nucleic(71) cDNA(70) Primer pair(1)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000021803 (Evidence)
Entrez Gene	170677 (Evidence)
UniGene	156506
DFCI	TC1578845
DoTS	DT.60100248
NIA Mouse Gene Index	U035424
Consensus CDS Project	CCDS26952.1
International Mouse Knockout Project Status	Cdhr1

Sequences

Length	Strain/Species
genomic	ENSMUSG00000021803	Ensembl Gene Model | MGI Sequence Detail	20462	C57BL/6J
transcript	ENSMUST00000022337	Ensembl | MGI Sequence Detail	4303	Not Applicable
polypeptide	ENSMUSP00000022337	Ensembl | MGI Sequence Detail	859	Not Applicable

All sequences(18) RefSeq(2) UniProt(2)

Polymorphisms

SNPs within 2kb(294 from dbSNP Build 137)

Protein-related information

Resource	ID	Description
InterPro	IPR002126	Cadherin
InterPro	IPR020894	Cadherin conserved site
InterPro	IPR015919	Cadherin-like
Protein Ontology	PR:000012351	protocadherin-21

References

(Earliest) J:73286 Rattner A, et al., A photoreceptor-specific cadherin is essential for the structural integrity of the outer segment and for photoreceptor survival. Neuron. 2001 Dec 6;32(5):775-86
(Latest) J:185648 Mizuguchi R, et al., Tbr2 deficiency in mitral and tufted cells disrupts excitatory-inhibitory balance of neural circuitry in the mouse olfactory bulb. J Neurosci. 2012 Jun 27;32(26):8831-44
All references(41)