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Dppa2 Gene Detail
Summary
  • Symbol
    Dppa2
  • Name
    developmental pluripotency associated 2
  • Synonyms
    2410088E07Rik, ECAT15-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2157523
    NCBI Gene: 73703
Location & Maps
more
  • Sequence Map
    Chr16:48310274-48319513 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      9240 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    DPPA2, developmental pluripotency associated 2
  • Vertebrate Orthologs
    6
  • Human Ortholog
    DPPA2, developmental pluripotency associated 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CT100, ECAT15-2, PESCRG1
  • Links
    NCBI Gene ID: 151871
    neXtProt AC: NX_Q7Z7J5

  • Chr Location
    3q13.13; chr3:109293788-109316535 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    15 phenotypes from multigenic genotypes
    6 phenotype references
  • All Mutations and Alleles
    47
  • Gene trapped
    44
  • Targeted
    3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 73703 NCBI Gene Model | MGI Sequence Detail 9240 C57BL/6J ±  kb
transcript NM_028615 RefSeq | MGI Sequence Detail 1941 Not Specified  
polypeptide Q9CWH0 UniProt | EBI | MGI Sequence Detail 301 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    53 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000006665 developmental pluripotency-associated protein 2
  • InterPro Domains
    IPR025892 Developmental pluripotency-associated protein 2/4, central domain
    IPR025891 Developmental pluripotency-associated protein 2/4, C-terminal domain
    IPR003034 SAP domain
Molecular
Reagents
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  • All nucleic 45
    cDNA 43
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
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MGI:1920953
References
more
  • Summaries
    All 34
    Developmental Gene Expression 6
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:196366 Krentz AD, et al., Interaction between DMRT1 function and genetic background modulates signaling and pluripotency to control tumor susceptibility in the fetal germ line. Dev Biol. 2013 May 1;377(1):67-78

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory