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Dppa2 Gene Detail
Summary
  • Symbol
    Dppa2
  • Name
    developmental pluripotency associated 2
  • Synonyms
    2410088E07Rik, ECAT15-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2157523
    NCBI Gene: 73703
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:48310274-48319513 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 30.75 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    53 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2157523
protein coding gene Chr16:48310274-48319723 (.)
129S1/SvImJ MGP_129S1SvImJ_G0022864
protein coding gene Chr16:47161865-47175097 (+)
A/J no annotation
AKR/J MGP_AKRJ_G0022802
protein coding gene Chr16:46589143-46598730 (+)
BALB/cJ MGP_BALBcJ_G0022831
protein coding gene Chr16:45129792-45143132 (+)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0023278
protein coding gene Chr16:48330129-48345461 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020791
protein coding gene Chr16:45237168-45247391 (+)
CAST/EiJ MGP_CASTEiJ_G0022120
protein coding gene Chr16:46922648-46932104 (+)
CBA/J MGP_CBAJ_G0022567
protein coding gene Chr16:50231435-50247358 (+)
DBA/2J MGP_DBA2J_G0022698
protein coding gene Chr16:44803275-44812773 (+)
FVB/NJ MGP_FVBNJ_G0022674
protein coding gene Chr16:44687544-44697677 (+)
LP/J MGP_LPJ_G0022766
protein coding gene Chr16:46915394-46930061 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022692
protein coding gene Chr16:49925912-49941453 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023293
protein coding gene Chr16:46580459-46589660 (+)
PWK/PhJ MGP_PWKPhJ_G0021860
protein coding gene Chr16:45154294-45165288 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021690
protein coding gene Chr16:46478770-46490598 (+)
WSB/EiJ MGP_WSBEiJ_G0022165
protein coding gene Chr16:46635081-46645309 (+)



Homology
more
  • Human Ortholog
    DPPA2, developmental pluripotency associated 2
  • Vertebrate Orthologs
    6
  • Human Ortholog
    DPPA2, developmental pluripotency associated 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CT100, ECAT15-2, PESCRG1
  • Links
    NCBI Gene ID: 151871
    neXtProt AC: NX_Q7Z7J5
    UniProt: Q7Z7J5

  • Chr Location
    3q13.13; chr3:109293788-109316553 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotypes from multigenic genotypes
    6 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 73703 NCBI Gene Model | MGI Sequence Detail 9240 C57BL/6J ±  kb
transcript NM_028615 RefSeq | MGI Sequence Detail 1941 Not Specified  
polypeptide Q9CWH0 UniProt | EBI | MGI Sequence Detail 301 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000006665 developmental pluripotency-associated protein 2
  • InterPro Domains
    IPR025892 Developmental pluripotency-associated protein 2/4, central domain
    IPR025891 Developmental pluripotency-associated protein 2/4, C-terminal domain
Molecular
Reagents
less
  • All nucleic 46
    cDNA 44
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGI:1920953
References
more
  • Summaries
    All 35
    Developmental Gene Expression 6
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:218442 Wang L, et al., LncRNA Dum interacts with Dnmts to regulate Dppa2 expression during myogenic differentiation and muscle regeneration. Cell Res. 2015 Mar;25(3):335-50

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory