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Stard4
Gene Detail
Symbol

Name
ID
Stard4
StAR-related lipid transfer (START) domain containing 4
MGI:2156764
Synonyms
4632419C16Rik, 9030213J02Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 18
18.18 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr18:33199355-33213862 bp, - strand
From VEGA annotation of GRCm38

  14508 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:15874  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: STARD4
Gene Tree: Stard4

Human
homologs
STARD4, StAR-related lipid transfer (START) domain containing 4
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 134429
neXtProt AC: NX_Q96DR4

Human Chr (Location): 5q22.1; chr5:111496033-111512536 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit decreased liver weight, body weight, and body length. Female mice homozygous for this allele exhibit decreased circulating cholesterol when fed a low cholesterol diet and altered bile composition when fed standard chow.
 
Interactions
Stard4 interacts with 365 markers (Mir1b, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process lipid transport, transport
Component cytoplasmic membrane-bounded vesicle, mitochondrion
Function cholesterol binding, lipid binding
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (46)    Tissues (38)    Images (9)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 46
cDNA source data(16)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(18) cDNA(18)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000028069 (Evidence)
Ensembl Gene Model ENSMUSG00000024378 (Evidence)
Entrez Gene 170459 (Evidence)
DFCI TC1647276, TC1599497, TC1576794
DoTS DT.101364274, DT.87070222, DT.489463, DT.94143847, DT.94143831, DT.94402803
NIA Mouse Gene Index U345283, U038294
PDB 1JSS
Consensus CDS Project CCDS29123.1
International Mouse Phenotyping Consortium Status Stard4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028069 VEGA Gene Model | MGI Sequence Detail 14508 C57BL/6J ±  kb
transcript OTTMUST00000069526 VEGA | MGI Sequence Detail 5097 Not Applicable 
polypeptide OTTMUSP00000035327 VEGA | MGI Sequence Detail 224 Not Applicable 

For the selected sequences
All sequences(62) RefSeq(6) UniProt(4)
Polymorphisms
SNPs within 2kb(153 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002913 START domain
InterPro IPR023393 START-like domain
Protein Ontology PR:000015719 StAR-related lipid transfer protein 4
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:177746 Rodriguez-Agudo D, et al., Subcellular localization and regulation of StarD4 protein in macrophages and fibroblasts. Biochim Biophys Acta. 2011 Oct;1811(10):597-606
All references(35)
Other
accession IDs
MGI:1924300, MGI:1924404, MGI:2147177, MGI:2147362

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory