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Slc2a10 Gene Detail
Summary
  • Symbol
    Slc2a10
  • Name
    solute carrier family 2 (facilitated glucose transporter), member 10
  • Synonyms
    Glut10
  • Feature Type
    protein coding gene
  • IDs
    MGI:2156687
    NCBI Gene: 170441
  • Gene Overview
    MyGene.info: SLC2A10
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:165503897-165519917 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 85.66 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    144 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2156687
protein coding gene Chr2:165503787-165519917 (.)
129S1/SvImJ MGP_129S1SvImJ_G0026896
protein coding gene Chr2:171069825-171083804 (+)
A/J MGP_AJ_G0026862
protein coding gene Chr2:164061094-164075145 (+)
AKR/J MGP_AKRJ_G0026835
protein coding gene Chr2:168952107-168968768 (+)
BALB/cJ MGP_BALBcJ_G0026871
protein coding gene Chr2:164417537-164432502 (+)
C3H/HeJ MGP_C3HHeJ_G0026615
protein coding gene Chr2:169298016-169313312 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027319
protein coding gene Chr2:176020204-176035652 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024691
protein coding gene Chr2:157460274-157472439 (+)
CAST/EiJ MGP_CASTEiJ_G0026073
protein coding gene Chr2:169733423-169751293 (+)
CBA/J MGP_CBAJ_G0026592
protein coding gene Chr2:182421509-182442828 (+)
DBA/2J MGP_DBA2J_G0026728
protein coding gene Chr2:163216669-163233254 (+)
FVB/NJ MGP_FVBNJ_G0026696
protein coding gene Chr2:161661288-161677374 (+)
LP/J MGP_LPJ_G0026830
protein coding gene Chr2:171111422-171127016 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026715
protein coding gene Chr2:185942629-185958324 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027375
protein coding gene Chr2:168844630-168863942 (+)
PWK/PhJ MGP_PWKPhJ_G0025808
protein coding gene Chr2:162827839-162839229 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025610
protein coding gene Chr2:167760765-167776633 (+)
WSB/EiJ MGP_WSBEiJ_G0026144
protein coding gene Chr2:169735964-169749776 (+)



Homology
more
  • Human Ortholog
    SLC2A10, solute carrier family 2 member 10
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SLC2A10, solute carrier family 2 member 10
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ATS, GLUT10
  • Links
    NCBI Gene ID: 81031
    neXtProt AC: NX_O95528
    UniProt: O95528

  • Chr Location
    20q13.12; chr20:46708358-46736347 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human SLC2A10 associations

Human Disease Mouse Models
      
IDs
View 2 "NOT" models
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    2 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 2 alleles in 3 genetic backgrounds
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice carrying ENU-induced mutations in this gene display thickening and aberrant vessel wall shape of large and medium size arteries, with significantly increased elastic fiber number and size. Cerebral arteries appear normal with no evidence of tortuosity, stenosis/dilatation or aneurysm.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 170441 NCBI Gene Model | MGI Sequence Detail 16021 C57BL/6J ±  kb
    transcript NM_130451 RefSeq | MGI Sequence Detail 3434 C57BL/6  
    polypeptide Q8VHD6 UniProt | EBI | MGI Sequence Detail 536 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000015059 solute carrier family 2, facilitated glucose transporter member 10
    • InterPro Domains
      IPR005828 Major facilitator, sugar transporter-like
      IPR020846 Major facilitator superfamily domain
      IPR036259 MFS transporter superfamily
      IPR003663 Sugar/inositol transporter
      IPR005829 Sugar transporter, conserved site
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 11
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1858383
    References
    more
    • Summaries
      All 30
      Developmental Gene Expression 2
      Diseases 1
      Gene Ontology 5
      Phenotypes 4
    • Earliest
      J:49040 Herron BJ, et al., Putative assignment of ESTs to the genetic map by use of the SSLP database. Mamm Genome. 1998 Dec;9(12):1072-4
    • Latest
      J:255520 Syu YW, et al., GLUT10 maintains the integrity of major arteries through regulation of redox homeostasis and mitochondrial function. Hum Mol Genet. 2018 Jan 15;27(2):307-321

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory