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Kcnh4
Gene Detail
Symbol

Name
ID
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
MGI:2156184
Synonyms
BEC2
Feature Type
protein coding gene
Genetic Map
Chromosome 11
63.57 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:100740376-100759942 bp, - strand
From VEGA annotation of GRCm38

  19567 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8180  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: KCNH4
Protein SuperFamily: potassium voltage-gated channel, subfamily H
Gene Tree: Kcnh4

Human
homologs
KCNH4, potassium channel, voltage gated eag related subfamily H, member 4
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 23415
neXtProt AC: NX_Q9UQ05

Human Synonyms: BEC2, ELK1, Kv12.3

Human Chr (Location): 17q21.2; chr17:42156892-42181278 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Genomic Mutations involving Kcnh4 (1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Kcnh4 interacts with 81 markers (Mir1a-1, Mir1a-2, Mir15a, ...)
Gene Ontology
(GO)
classifications
Expression
cDNA source data(4)
Other mouse links: GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(5) cDNA(4) Other(1)
Microarray probesets(1)
Other database
links
VEGA Gene Model OTTMUSG00000002129 (Evidence)
Ensembl Gene Model ENSMUSG00000035355 (Evidence)
Entrez Gene 380728 (Evidence)
UniGene 297539
DFCI TC1703652
DoTS DT.97390007
NIA Mouse Gene Index U169000
Consensus CDS Project CCDS36334.1
International Mouse Phenotyping Consortium Status Kcnh4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000002129 VEGA Gene Model | MGI Sequence Detail 19567 C57BL/6J ±  kb
transcript OTTMUST00000004331 VEGA | MGI Sequence Detail 3748 Not Applicable 
polypeptide OTTMUSP00000002055 VEGA | MGI Sequence Detail 1018 Not Applicable 

For the selected sequences
All sequences(25) RefSeq(4) UniProt(1)
Polymorphisms
SNPs within 2kb(64 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000595 Cyclic nucleotide-binding domain
InterPro IPR018490 Cyclic nucleotide-binding-like
InterPro IPR005821 Ion transport domain
InterPro IPR001610 PAC motif
InterPro IPR000700 PAS-associated, C-terminal
InterPro IPR000014 PAS domain
InterPro IPR003938 Potassium channel, voltage-dependent, EAG/ELK/ERG
InterPro IPR003950 Potassium channel, voltage-dependent, ELK
InterPro IPR014710 RmlC-like jelly roll fold
Protein Ontology PR:000000793 voltage-gated potassium channel KCNH4
References
(Earliest) J:73270 Cui Y, et al., The Stat3/5 locus encodes novel endoplasmic reticulum and helicase-like proteins that are preferentially expressed in normal and neoplastic mammary tissue. Genomics. 2001 Dec;78(3):129-34
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(20)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory