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Kcnh4 Gene Detail
Summary
  • Symbol
    Kcnh4
  • Name
    potassium voltage-gated channel, subfamily H (eag-related), member 4
  • Synonyms
    BEC2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2156184
    NCBI Gene: 380728
  • Gene Overview
    MyGene.info: KCNH4
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:100740376-100759942 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 63.57 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    63 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2156184
protein coding gene Chr11:100740376-100760176 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019168
protein coding gene Chr11:103512971-103532333 (-)
A/J MGP_AJ_G0019136
protein coding gene Chr11:99191428-99211029 (-)
AKR/J MGP_AKRJ_G0019105
protein coding gene Chr11:102270307-102291019 (-)
BALB/cJ MGP_BALBcJ_G0019110
protein coding gene Chr11:99678691-99698611 (-)
C3H/HeJ MGP_C3HHeJ_G0018919
protein coding gene Chr11:102435505-102456321 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019559
protein coding gene Chr11:106720200-106741326 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017185
protein coding gene Chr11:96608279-96627372 (-)
CAST/EiJ MGP_CASTEiJ_G0018473
protein coding gene Chr11:103416901-103441005 (-)
CBA/J MGP_CBAJ_G0018888
protein coding gene Chr11:111179127-111198710 (-)
DBA/2J MGP_DBA2J_G0019000
protein coding gene Chr11:98727836-98747813 (-)
FVB/NJ MGP_FVBNJ_G0018990
protein coding gene Chr11:98266311-98287963 (-)
LP/J MGP_LPJ_G0019069
protein coding gene Chr11:104071553-104091153 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019021
protein coding gene Chr11:110760982-110780594 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019597
protein coding gene Chr11:102587745-102607343 (-)
PWK/PhJ MGP_PWKPhJ_G0018236
protein coding gene Chr11:99766846-99786814 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018028
protein coding gene Chr11:102331485-102351140 (-)
WSB/EiJ MGP_WSBEiJ_G0018522
protein coding gene Chr11:102577546-102598827 (-)



Homology
more
  • Human Ortholog
    KCNH4, potassium voltage-gated channel subfamily H member 4
  • Vertebrate Orthologs
    9
  • Human Ortholog
    KCNH4, potassium voltage-gated channel subfamily H member 4
    Orthology source: HGNC, HomoloGene
  • Synonyms
    BEC2, ELK1, Kv12.3
  • Links
    NCBI Gene ID: 23415
    neXtProt AC: NX_Q9UQ05
    UniProt: Q9UQ05

  • Chr Location
    17q21.2; chr17:42156892-42181278 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035355 Ensembl Gene Model | MGI Sequence Detail 19567 C57BL/6J ±  kb
transcript ENSMUST00000107363 Ensembl | MGI Sequence Detail 3948 Not Applicable  
polypeptide ENSMUSP00000102986 Ensembl | MGI Sequence Detail 1018 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 1
References
more
  • Summaries
    All 27
    Gene Ontology 2
    Phenotypes 14
  • Earliest
    J:50799 Liu P, et al., Embryonic lethality and tumorigenesis caused by segmental aneuploidy on mouse chromosome 11. Genetics. 1998 Nov;150(3):1155-68
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory