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P2ry14
Gene Detail
 Symbol
Name
ID
P2ry14
purinergic receptor P2Y, G-protein coupled, 14
MGI:2155705
Synonyms A330108O13Rik, Gpr105, P2Y14
Feature Type protein coding gene
Genetic Map
Chromosome 3
28.96 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr3:59114626-59130624 bp, - strand
From Ensembl annotation of GRCm38

  15999 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:15769  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Protein SuperFamily: P2RY12-like receptor
Gene Tree: P2ry14

Human
homologs
Human Homolog P2RY14, purinergic receptor P2Y, G-protein coupled, 14
NCBI Gene ID 9934
neXtProt AC  NX_Q15391
Human Synonyms  BPR105, GPR105, P2Y14
Human Chr (Location)  3q24-q25.1; chr3:151212117-151279208 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele fail to exhibit increased glucose mediated forestomach muscle tension.
 
Interactions
P2ry14 interacts with 76 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process G-protein coupled receptor signaling pathway, immune response, ...
Component integral component of membrane, membrane, ...
Function G-protein coupled purinergic nucleotide receptor activity, G-protein coupled receptor activity, ...
External Resources: FuncBase
Expression
cDNA source data(14)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(14) cDNA(14)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000036381 (Evidence)
Entrez Gene140795 (Evidence)
UniGene439021
DFCITC1584484, TC1595743, TC1627920, TC1695913
DoTSDT.101248394, DT.101340137, DT.101364489, DT.102535067, DT.55265147, DT.97409290
Consensus CDS ProjectCCDS17371.1
International Mouse Knockout Project StatusP2ry14
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036381 Ensembl Gene Model | MGI Sequence Detail 15999 C57BL/6J ±  kb
transcript ENSMUST00000065220 Ensembl | MGI Sequence Detail 1671 Not Applicable 
polypeptide ENSMUSP00000066669 Ensembl | MGI Sequence Detail 338 Not Applicable 

For the selected sequences
All sequences(46) RefSeq(16) UniProt(2)
Polymorphisms SNPs within 2kb(140 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
InterPro IPR005466 UDP-glucose receptor
Protein Ontology PR:000001571 P2Y purinoceptor 14
References (Earliest) J:113918 Chambers JK, et al., A G protein-coupled receptor for UDP-glucose. J Biol Chem. 2000 Apr 14;275(15):10767-71
(Latest) J:189758 Xu J, et al., GPR105 ablation prevents inflammation and improves insulin sensitivity in mice with diet-induced obesity. J Immunol. 2012 Aug 15;189(4):1992-9
All references(33)
Other
accession IDs
MGI:2441794

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory