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Snx14 Gene Detail
Summary
  • Symbol
    Snx14
  • Name
    sorting nexin 14
  • Synonyms
    C330035N22Rik, YR-14
  • Feature Type
    protein coding gene
  • IDs
    MGI:2155664
    NCBI Gene: 244962
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:88376750-88438958 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 47.24 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    230 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2155664
protein coding gene Chr9:88376747-88444128 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035107
protein coding gene Chr9:89250584-89316678 (-)
A/J MGP_AJ_G0035088
protein coding gene Chr9:86136108-86198662 (-)
AKR/J MGP_AKRJ_G0035016
protein coding gene Chr9:88151513-88213503 (-)
BALB/cJ MGP_BALBcJ_G0035076
protein coding gene Chr9:85749966-85812057 (-)
C3H/HeJ MGP_C3HHeJ_G0034788
protein coding gene Chr9:88624533-88691383 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035600
protein coding gene Chr9:91660072-91726901 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032507
protein coding gene Chr9:84832498-84891461 (-)
CAST/EiJ MGP_CASTEiJ_G0034106
protein coding gene Chr9:89069980-89144154 (-)
CBA/J MGP_CBAJ_G0034761
protein coding gene Chr9:94871169-94940108 (-)
DBA/2J MGP_DBA2J_G0034919
protein coding gene Chr9:85662229-85724510 (-)
FVB/NJ MGP_FVBNJ_G0034862
protein coding gene Chr9:84712344-84775169 (-)
LP/J MGP_LPJ_G0035000
protein coding gene Chr9:89449268-89512507 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034904
protein coding gene Chr9:96502573-96571910 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035620
protein coding gene Chr9:88293141-88357994 (-)
PWK/PhJ MGP_PWKPhJ_G0033810
protein coding gene Chr9:85811701-85876920 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033646
protein coding gene Chr9:88463833-88531445 (-)
WSB/EiJ MGP_WSBEiJ_G0034223
protein coding gene Chr9:88324139-88392545 (-)



Homology
more
  • Human Ortholog
    SNX14, sorting nexin 14
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SNX14, sorting nexin 14
    Orthology source: HomoloGene, HGNC
  • Synonyms
    RGS-PX2, SCAR20
  • Links
    NCBI Gene ID: 57231
    neXtProt AC: NX_Q9Y5W7
    UniProt: Q9Y5W7

  • Chr Location
    6q14.3; chr6:85505496-85594156 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 17823
    1 human;1 mouse;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SNX14
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human SNX14 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032422 Ensembl Gene Model | MGI Sequence Detail 62209 C57BL/6J ±  kb
transcript ENSMUST00000174806 Ensembl | MGI Sequence Detail 3082 Not Applicable  
polypeptide ENSMUSP00000133533 Ensembl | MGI Sequence Detail 973 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 10
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2443156
References
more
  • Summaries
    All 25
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:70707 Carroll P, et al., Sorting nexin-14, a gene expressed in motoneurons trapped by an in vitro preselection method. Dev Dyn. 2001 Aug;221(4):431-42
  • Latest
    J:217344 Huang HS, et al., Snx14 regulates neuronal excitability, promotes synaptic transmission, and is imprinted in the brain of mice. PLoS One. 2014;9(5):e98383

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory