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Gpr6
Gene Detail
Symbol

Name
ID
Gpr6
G protein-coupled receptor 6
MGI:2155249
Feature Type
protein coding gene
Genetic Map
Chromosome 10
22.08 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr10:41069989-41072285 bp, - strand
From Ensembl annotation of GRCm38

  2297 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:38026  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: GPR6-like G protein-coupled receptor
Gene Tree: Gpr6

Human
homologs
Human Homolog GPR6, G protein-coupled receptor 6
NCBI Gene ID 2830
neXtProt AC  NX_P46095
Human Chr (Location)  6q21; chr6:109978256-109980720 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Targeted(7)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene does not appear to result in a phenotype.
 
Interactions
Gpr6 interacts with 158 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (6 records)
Data Summary: Results (193)    Tissues (125)    Images (33)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 93
In situ reporter (knock in) 42
Northern blot 8
RT-PCR 50
cDNA source data(5)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(9) cDNA(5) Primer pair(3) Other(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000046922 (Evidence)
Entrez Gene140741 (Evidence)
DFCITC1599369, TC1679659
DoTSDT.91403840
NIA Mouse Gene IndexU048652
Consensus CDS ProjectCCDS23802.1
International Mouse Knockout Project StatusGpr6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000046922 Ensembl Gene Model | MGI Sequence Detail 2297 C57BL/6J ±  kb
transcript ENSMUST00000061796 Ensembl | MGI Sequence Detail 1774 Not Applicable 
polypeptide ENSMUSP00000057323 Ensembl | MGI Sequence Detail 363 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(5) UniProt(3)
Polymorphisms
SNPs within 2kb(32 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000723 G protein-coupled receptor 3/6/12 orphan
InterPro IPR001151 G protein-coupled receptor 6
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
Protein Ontology PR:000001674 G-protein coupled receptor 6
References
(Earliest) J:72844 Chalhoub N, et al., Physical and transcriptional map of the mouse Chromosome 10 proximal region syntenic to human 6q16-q21. Mamm Genome. 2001 Dec;12(12):887-92
(Latest) J:206284 Lu KM, et al., Dual role for Islet-1 in promoting striatonigral and repressing striatopallidal genetic programs to specify striatonigral cell identity. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):E168-77
All references(36)
Other
accession IDs
MGI:2143693, MGI:2685079

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory