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Ankrd6 Gene Detail
Summary
  • Symbol
    Ankrd6
  • Name
    ankyrin repeat domain 6
  • Synonyms
    diversin
  • Feature Type
    protein coding gene
  • IDs
    MGI:2154278
    NCBI Gene: 140577
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:32804035-32950841 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 14.42 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    852 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2154278
protein coding gene Chr4:32804027-32950883 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028114
protein coding gene Chr4:30275275-30434930 (-)
A/J MGP_AJ_G0028072
protein coding gene Chr4:29200662-29348405 (-)
AKR/J MGP_AKRJ_G0028036
protein coding gene Chr4:29955645-30114709 (-)
BALB/cJ MGP_BALBcJ_G0028083
protein coding gene Chr4:29462239-29609986 (-)
C3H/HeJ MGP_C3HHeJ_G0027813
protein coding gene Chr4:30243063-30398430 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028525
protein coding gene Chr4:31464268-31627445 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025867
protein coding gene Chr4:27259923-27408973 (-)
CAST/EiJ MGP_CASTEiJ_G0027267
protein coding gene Chr4:30023463-30174068 (-)
CBA/J MGP_CBAJ_G0027785
protein coding gene Chr4:32472987-32653768 (-)
DBA/2J MGP_DBA2J_G0027929
protein coding gene Chr4:29207308-29354747 (-)
FVB/NJ MGP_FVBNJ_G0027894
protein coding gene Chr4:28626701-28775627 (-)
LP/J MGP_LPJ_G0028037
protein coding gene Chr4:30366984-30522453 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027927
protein coding gene Chr4:35060383-35227044 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028584
protein coding gene Chr4:29957275-30120189 (-)
PWK/PhJ MGP_PWKPhJ_G0026987
protein coding gene Chr4:29182332-29335238 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026815
protein coding gene Chr4:29841908-30000310 (-)
WSB/EiJ MGP_WSBEiJ_G0027344
protein coding gene Chr4:29969092-30123739 (-)



Homology
more
  • Human Ortholog
    ANKRD6, ankyrin repeat domain 6
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ANKRD6, ankyrin repeat domain 6
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 22881
    neXtProt AC: NX_Q9Y2G4
    UniProt: Q9Y2G4

  • Chr Location
    6q15; chr6:89433178-89633834 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 8967
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: ANKRD6
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    4 phenotypes from multigenic genotypes
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display sporadic disruption of utricle hair cell polarity but normal cochlear and vestibular hair cell morphology.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040183 Ensembl Gene Model | MGI Sequence Detail 146807 C57BL/6J ±  kb
transcript ENSMUST00000084750 Ensembl | MGI Sequence Detail 4444 Not Applicable  
polypeptide ENSMUSP00000081802 Ensembl | MGI Sequence Detail 712 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 49
    cDNA 48
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 36
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 12
  • Earliest
    J:78250 Tissir F, et al., Expression of the ankyrin repeat domain 6 gene (Ankrd6) during mouse brain development. Dev Dyn. 2002 Aug;224(4):465-9
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory