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Ehd2
Gene Detail
 Symbol
Name
ID
Ehd2
EH-domain containing 2
MGI:2154274
Synonyms C130052H20Rik, MGC:25606, MGC:38650
Feature Type protein coding gene
Genetic Map
Chromosome 7
8.65 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr7:15946977-15967567 bp, - strand
From VEGA annotation of GRCm38

  20591 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22825  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Gene Tree: Ehd2

Human
homologs
Human Homolog EHD2, EH-domain containing 2
NCBI Gene ID 30846
neXtProt AC  NX_Q9NZN4
Human Synonyms  PAST2
Human Chr (Location)  19q13.3; chr19:47713344-47743134 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ehd2 interacts with 301 markers (Mir1b, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (23 annotations)
Process cortical actin cytoskeleton organization, endocytic recycling, ...
Component caveola, endosome, ...
Function ATP binding, calcium ion binding, ...
External Resources: FuncBase
Expression
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(15) Genomic(3) cDNA(12)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000023141 (Evidence)
Ensembl Gene ModelENSMUSG00000074364 (Evidence)
Entrez Gene259300 (Evidence)
DFCITC1576444, TC1594899, TC1597416
DoTSDT.101232509, DT.101369074, DT.534116
NIA Mouse Gene IndexU028174, U059021
PDB2QPT, 4CID
Consensus CDS ProjectCCDS20842.1
International Mouse Knockout Project StatusEhd2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023141 VEGA Gene Model | MGI Sequence Detail 20591 C57BL/6J ±  kb
transcript OTTMUST00000055928 VEGA | MGI Sequence Detail 5100 Not Applicable 
polypeptide OTTMUSP00000026835 VEGA | MGI Sequence Detail 543 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(2) UniProt(4)
Polymorphisms SNPs within 2kb(55 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001401 Dynamin, GTPase domain
InterPro IPR018247 EF-Hand 1, calcium-binding site
InterPro IPR002048 EF-hand domain
InterPro IPR011992 EF-hand-like domain
InterPro IPR000261 EPS15 homology (EH)
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000006943 EH domain-containing protein 2
References (Earliest) J:76561 Chae TH, et al., Mapping of the mouse hyh gene to a YAC/BAC contig on proximal Chromosome 7. Mamm Genome. 2002 May;13(5):239-44
(Latest) J:201740 Ludwig A, et al., Molecular composition and ultrastructure of the caveolar coat complex. PLoS Biol. 2013 Aug;11(8):e1001640
All references(40)
Other
accession IDs
MGI:2387219, MGI:2443299

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory