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Scgb3a2 Gene Detail
Summary
  • Symbol
    Scgb3a2
  • Name
    secretoglobin, family 3A, member 2
  • Synonyms
    LuLeu1, UGRP1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2153470
    NCBI Gene: 117158
  • Gene Overview
    MyGene.info: SCGB3A2
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:43764289-43767399 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 23.49 cM, cytoband C-D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    65 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2153470
protein coding gene Chr18:43764281-43767399 (.)
129S1/SvImJ MGP_129S1SvImJ_G0024388
protein coding gene Chr18:42488045-42491156 (+)
A/J MGP_AJ_G0024355
protein coding gene Chr18:40991707-40994818 (+)
AKR/J MGP_AKRJ_G0024324
protein coding gene Chr18:42118631-42121742 (+)
BALB/cJ MGP_BALBcJ_G0024355
protein coding gene Chr18:41075753-41078864 (+)
C3H/HeJ MGP_C3HHeJ_G0024122
protein coding gene Chr18:42174257-42177368 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024799
protein coding gene Chr18:43974916-43978026 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022235
protein coding gene Chr18:40804800-40807921 (+)
CAST/EiJ MGP_CASTEiJ_G0023596
protein coding gene Chr18:42163557-42166668 (+)
CBA/J MGP_CBAJ_G0024091
protein coding gene Chr18:45203553-45206664 (+)
DBA/2J MGP_DBA2J_G0024221
protein coding gene Chr18:40587478-40590589 (+)
FVB/NJ MGP_FVBNJ_G0024187
protein coding gene Chr18:40185516-40188627 (+)
LP/J MGP_LPJ_G0024305
protein coding gene Chr18:42519679-42522790 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024218
protein coding gene Chr18:46500338-46503448 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024846
protein coding gene Chr18:42001980-42005090 (+)
PWK/PhJ MGP_PWKPhJ_G0023340
protein coding gene Chr18:40800613-40803730 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023145
protein coding gene Chr18:42257136-42260263 (+)
WSB/EiJ MGP_WSBEiJ_G0023659
protein coding gene Chr18:41913394-41916505 (+)



Homology
more
  • Human Ortholog
    SCGB3A2, secretoglobin family 3A member 2
  • Vertebrate Orthologs
    6
  • Human Ortholog
    SCGB3A2, secretoglobin family 3A member 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    LU103, pnSP-1, PNSP1, UGRP1
  • Links
    NCBI Gene ID: 117156
    neXtProt AC: NX_Q96PL1
    UniProt: Q96PL1

  • Chr Location
    5q32; chr5:147878711-147882193 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human SCGB3A2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 2 genetic backgrounds
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit background sensitive lung inflammatory response to ovalbumin exposure.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038791 Ensembl Gene Model | MGI Sequence Detail 3111 C57BL/6J ±  kb
transcript ENSMUST00000043803 Ensembl | MGI Sequence Detail 842 Not Applicable  
polypeptide ENSMUSP00000038872 Ensembl | MGI Sequence Detail 139 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR016126 Secretoglobin
Molecular
Reagents
less
  • All nucleic 18
    Genomic 3
    cDNA 12
    Primer pair 2
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 37
    Developmental Gene Expression 16
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:72388 Niimi T, et al., UGRP1, a Uteroglobin/Clara Cell Secretory Protein-Related Protein, Is a Novel Lung-Enriched Downstream Target Gene for the T/EBP/NKX2.1 Homeodomain Transcription Factor. Mol Endocrinol. 2001 Nov;15(11):2021-36
  • Latest
    J:240319 Stauber M, et al., Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory