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Rnf34 Gene Detail
Summary
  • Symbol
    Rnf34
  • Name
    ring finger protein 34
  • Synonyms
    MGC:7670, phafin 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2153340
    NCBI Gene: 80751
  • Gene Overview
    MyGene.info: RNF34
Location & Maps
more
  • Sequence Map
    Chr5:122850048-122871291 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      21244 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 62.62 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    RNF34, ring finger protein 34
  • Vertebrate Orthologs
    11
  • Human Ortholog
    RNF34, ring finger protein 34
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CARP1, CARP-1, hRFI, RFI, RIF, RIFF
  • Links
    NCBI Gene ID: 80196
    neXtProt AC: NX_Q969K3

  • Chr Location
    12q24.31; chr12:121400083-121424352 (+)  GRCh38.p2
  • HomoloGene
    Vertebrate Homology Class 11839
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;2 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: RNF34
  • Gene Tree
    Rnf34
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    19
  • Chemically induced (other)
    1
  • Gene trapped
    15
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Rnf34
  • Incidental Mutations
    Mutagenetix , APF
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    37
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    37
  • Tissues
    30
  • cDNA Data
    17
  • Literature Summary
    3
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000054579 VEGA Gene Model | MGI Sequence Detail 21244 C57BL/6J ±  kb
transcript OTTMUST00000135299 VEGA | MGI Sequence Detail 4440 Not Applicable  
polypeptide OTTMUSP00000071623 VEGA | MGI Sequence Detail 376 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    104 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 17

    Microarray probesets 4
Other
Accession IDs
less
MGI:2136842, MGI:2141146, MGI:2141205, MGI:2141347
References
more
  • Summaries
    All 35
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 11
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:212788 Wei P, et al., RNF34 is a cold-regulated E3 ubiquitin ligase for PGC-1alpha and modulates brown fat cell metabolism. Mol Cell Biol. 2012 Jan;32(2):266-75
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/27/2016
MGI 6.05 		The Jackson Laboratory