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Rnf34 Gene Detail
Summary
  • Symbol
    Rnf34
  • Name
    ring finger protein 34
  • Synonyms
    MGC:7670, phafin 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2153340
    NCBI Gene: 80751
  • Gene Overview
    MyGene.info: RNF34
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:122850162-122868945 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 62.62 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    100 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2153340
protein coding gene Chr5:122850048-122871291 (.)
129S1/SvImJ MGP_129S1SvImJ_G0030059
protein coding gene Chr5:126523382-126547458 (+)
A/J MGP_AJ_G0030024
protein coding gene Chr5:121269954-121291668 (+)
AKR/J MGP_AKRJ_G0029960
protein coding gene Chr5:125176945-125201262 (+)
BALB/cJ MGP_BALBcJ_G0030035
protein coding gene Chr5:122616987-122639039 (+)
C3H/HeJ MGP_C3HHeJ_G0029752
protein coding gene Chr5:125802493-125823256 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030488
protein coding gene Chr5:131390411-131415213 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027714
protein coding gene Chr5:115868824-115892743 (+)
CAST/EiJ MGP_CASTEiJ_G0029161
protein coding gene Chr5:124894619-124917130 (+)
CBA/J MGP_CBAJ_G0029722
protein coding gene Chr5:136539182-136564290 (+)
DBA/2J MGP_DBA2J_G0029872
protein coding gene Chr5:121327374-121350049 (+)
FVB/NJ MGP_FVBNJ_G0029828
protein coding gene Chr5:120325165-120346473 (+)
LP/J MGP_LPJ_G0029961
protein coding gene Chr5:127054541-127079780 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029859
protein coding gene Chr5:140230450-140254274 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030529
protein coding gene Chr5:124774871-124800927 (+)
PWK/PhJ MGP_PWKPhJ_G0028875
protein coding gene Chr5:120112421-120132684 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028712
protein coding gene Chr5:122481182-122503076 (+)
WSB/EiJ MGP_WSBEiJ_G0029236
protein coding gene Chr5:125444318-125467772 (+)



Homology
more
  • Human Ortholog
    RNF34, ring finger protein 34
  • Vertebrate Orthologs
    11
  • Human Ortholog
    RNF34, ring finger protein 34
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CARP1, CARP-1, hRFI, RFI, RIF, RIFF
  • Links
    NCBI Gene ID: 80196
    neXtProt AC: NX_Q969K3
    UniProt: Q969K3

  • Chr Location
    12q24.31; chr12:121400083-121424353 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 11839
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;2 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: RNF34
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 80751 NCBI Gene Model | MGI Sequence Detail 18784 C57BL/6J ±  kb
transcript NM_030564 RefSeq | MGI Sequence Detail 1980 Not Specified  
polypeptide Q99KR6 UniProt | EBI | MGI Sequence Detail 376 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 18

    Microarray probesets 4
Other
Accession IDs
less
MGI:2136842, MGI:2141146, MGI:2141205, MGI:2141347
References
more
  • Summaries
    All 37
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 11
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:212788 Wei P, et al., RNF34 is a cold-regulated E3 ubiquitin ligase for PGC-1alpha and modulates brown fat cell metabolism. Mol Cell Biol. 2012 Jan;32(2):266-75

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/27/2018
MGI 6.13
The Jackson Laboratory