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Cd300c2 Gene Detail
Summary
  • Symbol
    Cd300c2
  • Name
    CD300C molecule 2
  • Synonyms
    AF251705, Cd300d, Clm4, DIgR1, Igsf7, LMIR2, MAIR-II
  • Feature Type
    protein coding gene
  • IDs
    MGI:2153249
    NCBI Gene: 140497
  • Gene Overview
    MyGene.info: CD300C
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr11:114996721-115001880 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5160 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 80.57 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    CD300C, CD300c molecule
  • Vertebrate Orthologs
    15
  • Human Ortholog
    CD300C, CD300c molecule
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CLM-6, CMRF35, CMRF-35, CMRF35A, CMRF-35A, CMRF35A1, CMRF35-A1, IGSF16, LIR
  • Links
    NCBI Gene ID: 10871
    neXtProt AC: NX_Q08708
    UniProt: Q08708

  • Chr Location
    17q25.1; chr17:74534359-74546171 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit increased stimulated B cell proliferation.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003604 VEGA Gene Model | MGI Sequence Detail 5160 C57BL/6J ±  kb
transcript OTTMUST00000007758 VEGA | MGI Sequence Detail 1187 Not Applicable  
polypeptide OTTMUSP00000003769 VEGA | MGI Sequence Detail 228 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    100 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:71672 Luo K, et al., DIgR1, a novel membrane receptor of the immunoglobulin gene superfamily, is preferentially expressed by antigen-presenting cells. Biochem Biophys Res Commun. 2001 Sep 14;287(1):35-41
  • Latest
    J:233118 Abdallah BM, et al., DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice. J Bone Miner Res. 2011 Jul;26(7):1457-71

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory