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Mrps6 Gene Detail
Summary
  • Symbol
    Mrps6
  • Name
    mitochondrial ribosomal protein S6
  • Feature Type
    protein coding gene
  • IDs
    MGI:2153111
    NCBI Gene: 121022
  • Gene Overview
    MyGene.info: MRPS6
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:92058336-92112227 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 53.44 cM, cytoband C4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    186 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2153111
protein coding gene Chr16:92058270-92112227 (.)
129S1/SvImJ MGP_129S1SvImJ_G0023051
protein coding gene Chr16:93122115-93176987 (+)
A/J MGP_AJ_G0023019
protein coding gene Chr16:88759625-88813587 (+)
AKR/J MGP_AKRJ_G0022989
protein coding gene Chr16:91446171-91504757 (+)
BALB/cJ MGP_BALBcJ_G0023021
protein coding gene Chr16:89291263-89345154 (+)
C3H/HeJ MGP_C3HHeJ_G0022782
protein coding gene Chr16:92010314-92064082 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023468
protein coding gene Chr16:96104626-96159649 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020970
protein coding gene Chr16:86445592-86497053 (+)
CAST/EiJ MGP_CASTEiJ_G0022301
protein coding gene Chr16:92587724-92644871 (+)
CBA/J MGP_CBAJ_G0022751
protein coding gene Chr16:100222900-100279130 (+)
DBA/2J MGP_DBA2J_G0022885
protein coding gene Chr16:88667746-88721856 (+)
FVB/NJ MGP_FVBNJ_G0022859
protein coding gene Chr16:87792302-87845963 (+)
LP/J MGP_LPJ_G0022955
protein coding gene Chr16:92806997-92864267 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022880
protein coding gene Chr16:104749905-104807092 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023486
protein coding gene Chr16:91969903-92023556 (+)
PWK/PhJ MGP_PWKPhJ_G0022046
protein coding gene Chr16:88850016-88903987 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021876
protein coding gene Chr16:91537738-91591720 (+)
WSB/EiJ MGP_WSBEiJ_G0022353
protein coding gene Chr16:92212267-92265813 (+)



Homology
more
  • Human Ortholog
    MRPS6, mitochondrial ribosomal protein S6
  • Vertebrate Orthologs
    8
  • Human Ortholog
    MRPS6, mitochondrial ribosomal protein S6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C21orf101, MRP-S6, RPMS6, S6mt
  • Links
    NCBI Gene ID: 64968
    neXtProt AC: NX_P82932
    UniProt: P82932

  • Chr Location
    21q22.11; chr21:34073523-34143034 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 121022 NCBI Gene Model | MGI Sequence Detail 53892 C57BL/6J ±  kb
transcript NM_080456 RefSeq | MGI Sequence Detail 795 FVB/N  
polypeptide P58064 UniProt | EBI | MGI Sequence Detail 125 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 10
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGI:2146610
References
more
  • Summaries
    All 38
    Developmental Gene Expression 6
    Gene Ontology 8
    Phenotypes 7
  • Earliest
    J:72140 Suzuki T, et al., Proteomic analysis of the mammalian mitochondrial ribosome. Identification of protein components in the 28 S small subunit. J Biol Chem. 2001 Aug 31;276(35):33181-95
  • Latest
    J:262380 Watson-Scales S, et al., Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration. PLoS Genet. 2018 May;14(5):e1007383

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory