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Trim37
Gene Detail
Symbol

Name
ID
Trim37
tripartite motif-containing 37
MGI:2153072
Synonyms
1110032A10Rik, 2810004E07Rik, MUL, TEF3
Feature Type
protein coding gene
Genetic Map
Chromosome 11
51.93 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:87127077-87220683 bp, + strand
From VEGA annotation of GRCm38

  93607 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9084  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: TRIM37
Gene Tree: Trim37

Human
homologs
TRIM37, tripartite motif containing 37
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 4591
neXtProt AC: NX_O94972

Human Synonyms: MUL, POB1, TEF3

Human Chr (Location): 17q23.2; chr17:58982638-59106905 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human TRIM37

Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(10) Targeted(1)
Genomic Mutations involving Trim37 (1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Trim37 interacts with 311 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (36 annotations)
Process aggresome assembly, histone H2A-K119 monoubiquitination, ...
Component aggresome, cytoplasm, ...
Function chromatin binding, coenzyme F420-0 gamma-glutamyl ligase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (87)    Tissues (48)    Images (17)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 87
cDNA source data(200)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase trim37    NEW 
Molecular
reagents
All nucleic(201) cDNA(201)
Microarray probesets(9)
Other database
links
VEGA Gene Model OTTMUSG00000001222 (Evidence)
Ensembl Gene Model ENSMUSG00000018548 (Evidence)
Entrez Gene 68729 (Evidence)
UniGene 17436
DFCI TC1677094, TC1671847, TC1572913
DoTS DT.91318458, DT.531684, DT.110518049, DT.101738700
NIA Mouse Gene Index U013134, U067664
EC 6.3.2.-
Consensus CDS Project CCDS25210.1
International Mouse Phenotyping Consortium Status Trim37
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001222 VEGA Gene Model | MGI Sequence Detail 93607 C57BL/6J ±  kb
transcript OTTMUST00000002445 VEGA | MGI Sequence Detail 5632 Not Applicable 
polypeptide OTTMUSP00000001205 VEGA | MGI Sequence Detail 961 Not Applicable 

For the selected sequences
All sequences(80) RefSeq(22) UniProt(3)
Polymorphisms
SNPs within 2kb(255 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003649 B-box, C-terminal
InterPro IPR002083 MATH
InterPro IPR008974 TRAF-like
InterPro IPR000315 Zinc finger, B-box
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
InterPro IPR001841 Zinc finger, RING-type
Protein Ontology PR:000030304 E3 ubiquitin-protein ligase TRIM37
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:217377 Bhatnagar S, et al., TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein. Nature. 2014 Dec 4;516(7529):116-20
All references(41)
Other
accession IDs
MGI:1915979, MGI:1919603, MGI:2144298, MGI:2144435

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory