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Elmo2
Gene Detail
Symbol

Name
ID
Elmo2
engulfment and cell motility 2
MGI:2153045
Synonyms
1190002F24Rik, CED-12, mKIAA1834
Feature Type
protein coding gene
Genetic Map
Chromosome 2
85.53 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:165288031-165326479 bp, - strand
From VEGA annotation of GRCm38

  38449 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:44338  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: ELMO2
Gene Tree: Elmo2

Human
homologs
ELMO2, engulfment and cell motility 2
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 63916
neXtProt AC: NX_Q96JJ3

Human Synonyms: CED12, CED-12, ELMO-2

Human Chr (Location): 20q13; chr20:46366049-46407051 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(2) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Elmo2 interacts with 274 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process apoptotic process, cell-cell adhesion, ...
Component cytoplasm, cytosol, ...
Function receptor tyrosine kinase binding, SH3 domain binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (64)    Tissues (42)    Images (13)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 62
RT-PCR 2
cDNA source data(15)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase elmo2    NEW 
Molecular
reagents
All nucleic(18) cDNA(17) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000001171 (Evidence)
Ensembl Gene Model ENSMUSG00000017670 (Evidence)
Entrez Gene 140579 (Evidence)
DFCI TC1601016, TC1597974, TC1591998, TC1597257, TC1591128, TC1572619
DoTS DT.491660, DT.110663014, DT.103568399, DT.101320654, DT.101283027, DT.101249901, DT.97354249, DT.97354945
NIA Mouse Gene Index U023659
Consensus CDS Project CCDS17075.1, CCDS17076.1, CCDS17077.1
International Mouse Phenotyping Consortium Status Elmo2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001171 VEGA Gene Model | MGI Sequence Detail 38449 C57BL/6J ±  kb
transcript OTTMUST00000040174 VEGA | MGI Sequence Detail 3052 Not Applicable 
polypeptide OTTMUSP00000017933 VEGA | MGI Sequence Detail 798 Not Applicable 

For the selected sequences
All sequences(116) RefSeq(17) UniProt(6)
Polymorphisms
SNPs within 2kb(337 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011989 Armadillo-like helical
InterPro IPR016024 Armadillo-type fold
InterPro IPR024574 Domain of unknown function DUF3361
InterPro IPR006816 Engulfment/cell motility, ELMO
InterPro IPR011993 Pleckstrin homology-like domain
Protein Ontology PR:000007032 engulfment and cell motility protein 2
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(31)
Other
accession IDs
MGI:1921247

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory