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Colec12 Gene Detail
Summary
  • Symbol
    Colec12
  • Name
    collectin sub-family member 12
  • Synonyms
    CL-P1, Scara4, SRCL
  • Feature Type
    protein coding gene
  • IDs
    MGI:2152907
    NCBI Gene: 140792
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:9707648-9877995 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 4.91 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    571 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2152907
protein coding gene Chr18:9707595-9882644 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024142
protein coding gene Chr18:6622310-6812056 (+)
A/J MGP_AJ_G0024104
protein coding gene Chr18:6589605-6758757 (+)
AKR/J MGP_AKRJ_G0024071
protein coding gene Chr18:6751450-6927464 (+)
BALB/cJ MGP_BALBcJ_G0024103
protein coding gene Chr18:6564078-6741019 (+)
C3H/HeJ MGP_C3HHeJ_G0023870
protein coding gene Chr18:6642772-6820764 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024548
protein coding gene Chr18:7030978-7209409 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021987
protein coding gene Chr18:6134467-6308059 (+)
CAST/EiJ MGP_CASTEiJ_G0023347
protein coding gene Chr18:6602458-6776186 (+)
CBA/J MGP_CBAJ_G0023842
protein coding gene Chr18:7031697-7230821 (+)
DBA/2J MGP_DBA2J_G0023971
protein coding gene Chr18:6437762-6612167 (+)
FVB/NJ MGP_FVBNJ_G0023936
protein coding gene Chr18:6398980-6573218 (+)
LP/J MGP_LPJ_G0024054
protein coding gene Chr18:6707350-6892189 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023965
protein coding gene Chr18:7218678-7413913 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024594
protein coding gene Chr18:6571347-6754295 (+)
PWK/PhJ MGP_PWKPhJ_G0023092
protein coding gene Chr18:6472452-6648932 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022903
protein coding gene Chr18:6872706-7056719 (+)
WSB/EiJ MGP_WSBEiJ_G0023413
protein coding gene Chr18:6560468-6745275 (+)



Homology
more
  • Human Ortholog
    COLEC12, collectin subfamily member 12
  • Vertebrate Orthologs
    10
  • Human Ortholog
    COLEC12, collectin subfamily member 12
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CLP1, NSR2, SCARA4, SRCL
  • Links
    NCBI Gene ID: 81035
    neXtProt AC: NX_Q5KU26
    UniProt: Q5KU26

  • Chr Location
    18p11.32; chr18:319355-500729 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 140792 NCBI Gene Model | MGI Sequence Detail 170348 C57BL/6J ±  kb
transcript NM_130449 RefSeq | MGI Sequence Detail 3322 C57BL/6  
polypeptide Q8K4Q8 UniProt | EBI | MGI Sequence Detail 742 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 49
    cDNA 49

    Microarray probesets 3
References
more
  • Summaries
    All 31
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:72785 Ohtani K, et al., The membrane-type collectin CL-P1 is a scavenger receptor on vascular endothelial cells. J Biol Chem. 2001 Nov 23;276(47):44222-8
  • Latest
    J:265604 Naba A, et al., The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices. Mol Cell Proteomics. 2012 Apr;11(4):M111.014647

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory