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Asb7 Gene Detail
Summary
  • Symbol
    Asb7
  • Name
    ankyrin repeat and SOCS box-containing 7
  • Synonyms
    Asb-7, D030055C23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2152835
    NCBI Gene: 117589
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:66644565-66689596 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 36.03 cM, cytoband C
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    334 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2152835
 protein coding gene Chr7:66644565-66689649 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032353
 protein coding gene Chr7:67877071-67922860 (-)
A/J MGP_AJ_G0032332
 protein coding gene Chr7:66482083-66527087 (-)
AKR/J MGP_AKRJ_G0032268
 protein coding gene Chr7:67897863-67942861 (-)
BALB/cJ MGP_BALBcJ_G0032344
 protein coding gene Chr7:66222113-66267464 (-)
C3H/HeJ MGP_C3HHeJ_G0032057
 protein coding gene Chr7:68568653-68613780 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032836
 protein coding gene Chr7:70788704-70835206 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029843
 protein coding gene Chr7:69376809-69422534 (-)
CAST/EiJ MGP_CASTEiJ_G0031385
 protein coding gene Chr7:59250959-59295883 (-)
CBA/J MGP_CBAJ_G0032023
 protein coding gene Chr7:73005555-73050566 (-)
DBA/2J MGP_DBA2J_G0032178
 protein coding gene Chr7:65203793-65248692 (-)
FVB/NJ MGP_FVBNJ_G0032133
 protein coding gene Chr7:65330278-65375151 (-)
LP/J MGP_LPJ_G0032259
 protein coding gene Chr7:69095090-69139980 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032170
 protein coding gene Chr7:73245885-73290921 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032854
 protein coding gene Chr7:67250591-67295745 (-)
PWK/PhJ MGP_PWKPhJ_G0031105
 protein coding gene Chr7:58245568-58290642 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030946
 protein coding gene Chr7:54290770-54335774 (-)
WSB/EiJ MGP_WSBEiJ_G0031503
 protein coding gene Chr7:67596006-67640950 (-)



Homology
more
  • Human Ortholog
    ASB7, ankyrin repeat and SOCS box containing 7
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ASB7, ankyrin repeat and SOCS box containing 7
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 140460
    neXtProt AC: NX_Q9H672
    UniProt: Q9H672

  • Chr Location
    chr15:100602550-100651701 (+)  GRCh38.p7
  • HomoloGene
    Vertebrate Homology Class 34130
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: ASB7
  • Gene Tree
    Asb7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    2
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Asb7
  • Incidental Mutations
    Mutagenetix , APF
  • Find Mice (IMSR)
    4 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    12
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030509 Ensembl Gene Model | MGI Sequence Detail 45032 C57BL/6J ±  kb
transcript ENSMUST00000124899 Ensembl | MGI Sequence Detail 4928 Not Applicable  
polypeptide ENSMUSP00000122395 Ensembl | MGI Sequence Detail 318 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 8
Other
Accession IDs
less
MGI:2141960, MGI:2441936
References
more
  • Summaries
    All 36
    Gene Ontology 1
    Phenotypes 13
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/10/2019
MGI 6.14 		The Jackson Laboratory