Asb7 Gene Detail

Summary

• Symbol
  Asb7
• Name
  ankyrin repeat and SOCS box-containing 7
• Synonyms
  Asb-7, D030055C23Rik

• Feature Type
  protein coding gene
• IDs
  MGI:2152835
  NCBI Gene: 117589

Location & Maps

• Sequence Map
  Chr7:66644565-66689596 bp, - strand
• From VEGA annotation of GRCm38
  

  Mouse Genome Browser
  
  

• Download
  Sequence
    45032 bp   ±  kb flank
  
  
• Genome Browsers
  VEGA | Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 7, 36.03 cM, cytoband C
• Mapping Data
  3 experiments

Homology

• Human Ortholog
  ASB7, ankyrin repeat and SOCS box containing 7

• Vertebrate Orthologs
  10

• Human Ortholog
  ASB7, ankyrin repeat and SOCS box containing 7
  Orthology source: HomoloGene, HGNC
• Links
  HGNC:17182

  NCBI Gene ID: 140460

  neXtProt AC: NX_Q9H672

  UniProt: Q9H672

  
  
• Chr Location
  chr15:100602550-100651701 (+)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 34130
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  
• HCOP
  human homology predictions: ASB7
• Gene Tree
  Asb7
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  12 phenotype references
  

• All Mutations and Alleles
  6
• Chemically induced (other)
  1
• Gene trapped
  2
• Radiation induced
  1
• Targeted
  2
• Genomic Mutations
  2 involving Asb7
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  9 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  1
• GO References
  1

• External Resources
  FuncBase

Expression

• cDNA Data
  11

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase asb7
  ZFIN asb7

Interactions

• Asb7 interacts with 364 markers (Mir7-1, Mir7-2, Mir7b, ...) View All

Sequences &
Gene Models

• All Sequences
  45
• RefSeq
  9
• UniProt
  3
• CCDS
  CCDS21346.1

• VEGA
  OTTMUSG00000028988 (Evidence)
• Ensembl
  ENSMUSG00000030509 (Evidence)
• NCBI Gene
  117589

Representative Sequences			Length	Strain/Species
genomic	OTTMUSG00000028988	VEGA Gene Model | MGI Sequence Detail	45032	C57BL/6J
transcript	OTTMUST00000071880	VEGA | MGI Sequence Detail	4928	Not Applicable
polypeptide	OTTMUSP00000036910	VEGA | MGI Sequence Detail	318	Not Applicable

Polymorphisms

• SNPs within 2kb
  334 from dbSNP Build 142

Protein
Information

• UniProt
  3 Sequences
• Protein Ontology
  PR:000004356 ankyrin repeat and SOCS box protein 7
  (term hierarchy)
• InterPro Domains
  IPR002110 Ankyrin repeat
  IPR020683 Ankyrin repeat-containing domain
  IPR001496 SOCS box domain

Molecular
Reagents

• All nucleic 11

  cDNA 11

  
  

  Microarray probesets 8

Other
Accession IDs

MGI:2141960, MGI:2441936

References

• Summaries
  All 34

  Gene Ontology 1

  Phenotypes 12
• Earliest
  J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
• Latest
  J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42