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Asb7 Gene Detail
Summary
  • Symbol
    Asb7
  • Name
    ankyrin repeat and SOCS box-containing 7
  • Synonyms
    Asb-7, D030055C23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2152835
    NCBI Gene: 117589
Location & Maps
more
  • Sequence Map
    Chr7:66644565-66689596 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      45032 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 36.03 cM, cytoband C
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    ASB7, ankyrin repeat and SOCS box containing 7
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ASB7, ankyrin repeat and SOCS box containing 7
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 140460
    neXtProt AC: NX_Q9H672

  • Chr Location
    chr15:100602550-100651701 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 34130
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: ASB7
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Asb7
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028988 VEGA Gene Model | MGI Sequence Detail 45032 C57BL/6J ±  kb
transcript OTTMUST00000071880 VEGA | MGI Sequence Detail 4928 Not Applicable  
polypeptide OTTMUSP00000036910 VEGA | MGI Sequence Detail 318 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    334 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000004356 ankyrin repeat and SOCS box protein 7
  • InterPro Domains
    IPR002110 Ankyrin repeat
    IPR020683 Ankyrin repeat-containing domain
    IPR001496 SOCS box domain
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 8
Other
Accession IDs
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MGI:2141960, MGI:2441936
References
more
  • Summaries
    All 25
    Gene Ontology 1
    Phenotypes 12
  • Earliest
    J:71266 Kile BT, et al., Functional analysis of Asb-1 using genetic modification in mice. Mol Cell Biol. 2001 Sep;21(18):6189-97
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory