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Asb7 Gene Detail
Summary
  • Symbol
    Asb7
  • Name
    ankyrin repeat and SOCS box-containing 7
  • Synonyms
    Asb-7, D030055C23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2152835
    NCBI Gene: 117589
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:66294313-66339344 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 36.03 cM, cytoband C
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    325 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2152835
protein coding gene Chr7:66294220-66339601 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032353
protein coding gene Chr7:67877071-67922860 (-)
A/J MGP_AJ_G0032332
protein coding gene Chr7:66482083-66527087 (-)
AKR/J MGP_AKRJ_G0032268
protein coding gene Chr7:67897863-67942861 (-)
BALB/cJ MGP_BALBcJ_G0032344
protein coding gene Chr7:66222113-66267464 (-)
C3H/HeJ MGP_C3HHeJ_G0032057
protein coding gene Chr7:68568653-68613780 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032836
protein coding gene Chr7:70788704-70835206 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029843
protein coding gene Chr7:69376809-69422534 (-)
CAST/EiJ MGP_CASTEiJ_G0031385
protein coding gene Chr7:59250959-59295883 (-)
CBA/J MGP_CBAJ_G0032023
protein coding gene Chr7:73005555-73050566 (-)
DBA/2J MGP_DBA2J_G0032178
protein coding gene Chr7:65203793-65248692 (-)
FVB/NJ MGP_FVBNJ_G0032133
protein coding gene Chr7:65330278-65375151 (-)
LP/J MGP_LPJ_G0032259
protein coding gene Chr7:69095090-69139980 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032170
protein coding gene Chr7:73245885-73290921 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032854
protein coding gene Chr7:67250591-67295745 (-)
PWK/PhJ MGP_PWKPhJ_G0031105
protein coding gene Chr7:58245568-58290642 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030946
protein coding gene Chr7:54290770-54335774 (-)
WSB/EiJ MGP_WSBEiJ_G0031503
protein coding gene Chr7:67596006-67640950 (-)



Homology
more
  • Human Ortholog
    ASB7, ankyrin repeat and SOCS box containing 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ASB7, ankyrin repeat and SOCS box containing 7
  • Links
    NCBI Gene ID: 140460
    neXtProt AC: NX_Q9H672
    UniProt: Q9H672

  • Chr Location
    chr15:100602550-100651701 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    20 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000030509 Ensembl Gene Model | MGI Sequence Detail 45032 C57BL/6J ±  kb
    transcript ENSMUST00000124899 Ensembl | MGI Sequence Detail 4928 Not Applicable  
    polypeptide ENSMUSP00000122395 Ensembl | MGI Sequence Detail 318 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 12

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGI:2141960, MGI:2441936
    References
    more
    • Summaries
      All 37
      Gene Ontology 1
      Phenotypes 13
    • Earliest
      J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
    • Latest
      J:321561 Liu Y, et al., ASB7 Is a Novel Regulator of Cytoskeletal Organization During Oocyte Maturation. Front Cell Dev Biol. 2020;8:595917

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    08/03/2022
    MGI 6.21
    The Jackson Laboratory