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Asb7 Gene Detail
Summary
  • Symbol
    Asb7
  • Name
    ankyrin repeat and SOCS box-containing 7
  • Synonyms
    Asb-7, D030055C23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2152835
    NCBI Gene: 117589
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:66294313-66339344 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 36.03 cM, cytoband C
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2169 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2152835
 protein coding gene Chr7:66294220-66339601 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032353
 protein coding gene Chr7:67877071-67922860 (-)
A/J MGP_AJ_G0032332
 protein coding gene Chr7:66482083-66527087 (-)
AKR/J MGP_AKRJ_G0032268
 protein coding gene Chr7:67897863-67942861 (-)
BALB/cJ MGP_BALBcJ_G0032344
 protein coding gene Chr7:66222113-66267464 (-)
C3H/HeJ MGP_C3HHeJ_G0032057
 protein coding gene Chr7:68568653-68613780 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032836
 protein coding gene Chr7:70788704-70835206 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029843
 protein coding gene Chr7:69376809-69422534 (-)
CAST/EiJ MGP_CASTEiJ_G0031385
 protein coding gene Chr7:59250959-59295883 (-)
CBA/J MGP_CBAJ_G0032023
 protein coding gene Chr7:73005555-73050566 (-)
DBA/2J MGP_DBA2J_G0032178
 protein coding gene Chr7:65203793-65248692 (-)
FVB/NJ MGP_FVBNJ_G0032133
 protein coding gene Chr7:65330278-65375151 (-)
LP/J MGP_LPJ_G0032259
 protein coding gene Chr7:69095090-69139980 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032170
 protein coding gene Chr7:73245885-73290921 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032854
 protein coding gene Chr7:67250591-67295745 (-)
PWK/PhJ MGP_PWKPhJ_G0031105
 protein coding gene Chr7:58245568-58290642 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030946
 protein coding gene Chr7:54290770-54335774 (-)
WSB/EiJ MGP_WSBEiJ_G0031503
 protein coding gene Chr7:67596006-67640950 (-)



Homology
more
  • Human Ortholog
    ASB7, ankyrin repeat and SOCS box containing 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ASB7, ankyrin repeat and SOCS box containing 7
  • Links
    NCBI Gene ID: 140460
    UniProt: Q9H672

  • Chr Location
    chr15:100602589-100651701 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    21 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    12
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000030509 Ensembl Gene Model | MGI Sequence Detail 45032 C57BL/6J ±  kb
    transcript ENSMUST00000124899 Ensembl | MGI Sequence Detail 4928 Not Applicable  
    polypeptide ENSMUSP00000122395 Ensembl | MGI Sequence Detail 318 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 12

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGI:2141960, MGI:2441936
    References
    more
    • Summaries
      All 42
      Gene Ontology 4
      Phenotypes 15
    • Earliest
      J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/25/2025
    MGI 6.24     		The Jackson Laboratory