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Creld1 Gene Detail
Summary
  • Symbol
    Creld1
  • Name
    cysteine-rich with EGF-like domains 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2152539
    NCBI Gene: 171508
  • Gene Overview
    MyGene.info: CRELD1
Location & Maps
more
  • Sequence Map
    Chr6:113483297-113493343 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      10047 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    CRELD1, cysteine rich with EGF like domains 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CRELD1, cysteine rich with EGF like domains 1
    Orthology source: HomoloGene
  • Synonyms
    AVSD2, CIRRIN
  • Links
    NCBI Gene ID: 78987
    neXtProt AC: NX_Q96HD1

  • Chr Location
    3p25.3; chr3:9933788-9945413 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human CRELD1 associations

Human Disease Mouse Models
       Atrioventricular Septal Defect, Susceptibility to, 2; AVSD2   OMIM: 606217
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    16
  • Gene trapped
    11
  • Spontaneous
    1
  • Targeted
    4
  • Genomic Mutations
    1 involving Creld1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023299 VEGA Gene Model | MGI Sequence Detail 10047 C57BL/6J ±  kb
transcript OTTMUST00000056426 VEGA | MGI Sequence Detail 2306 Not Applicable  
polypeptide OTTMUSP00000027118 VEGA | MGI Sequence Detail 420 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    62 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000031551 cysteine-rich with EGF-like domain protein 1
  • InterPro Domains
    IPR021852 Domain of unknown function DUF3456
    IPR018097 EGF-like calcium-binding, conserved site
    IPR001881 EGF-like calcium-binding domain
    IPR013032 EGF-like, conserved site
    IPR000742 EGF-like domain
    IPR000152 EGF-type aspartate/asparagine hydroxylation site
    IPR006212 Furin-like repeat
    IPR009030 Growth factor receptor cysteine-rich domain
    IPR002049 Laminin EGF domain
Molecular
Reagents
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  • All nucleic 81
    cDNA 81

    Microarray probesets 2
Other
Accession IDs
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MGI:2141490
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 12
  • Earliest
    J:78392 Rupp PA, et al., Identification, genomic organization and mRNA expression of CRELD1, the founding member of a unique family of matricellular proteins. Gene. 2002 Jun 26;293(1-2):47-57
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory