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Ipo7 Gene Detail
Summary
  • Symbol
    Ipo7
  • Name
    importin 7
  • Synonyms
    A330055O14Rik, Imp7, RanBP7
  • Feature Type
    protein coding gene
  • IDs
    MGI:2152414
    NCBI Gene: 233726
  • Gene Overview
    MyGene.info: IPO7
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:110018315-110056609 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 57.70 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    242 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2152414
protein coding gene Chr7:110018274-110056609 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032852
protein coding gene Chr7:113481645-113518409 (+)
A/J MGP_AJ_G0032836
protein coding gene Chr7:110666339-110703134 (+)
AKR/J MGP_AKRJ_G0032767
protein coding gene Chr7:113451498-113488227 (+)
BALB/cJ MGP_BALBcJ_G0032840
protein coding gene Chr7:110365002-110401584 (+)
C3H/HeJ MGP_C3HHeJ_G0032550
protein coding gene Chr7:113480970-113517629 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033346
protein coding gene Chr7:118182644-118222893 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030319
protein coding gene Chr7:112240398-112280266 (+)
CAST/EiJ MGP_CASTEiJ_G0031878
protein coding gene Chr7:105017371-105058397 (+)
CBA/J MGP_CBAJ_G0032523
protein coding gene Chr7:122044794-122083794 (+)
DBA/2J MGP_DBA2J_G0032675
protein coding gene Chr7:108774671-108811719 (+)
FVB/NJ MGP_FVBNJ_G0032628
protein coding gene Chr7:108630117-108667457 (+)
LP/J MGP_LPJ_G0032769
protein coding gene Chr7:115011442-115049005 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032660
protein coding gene Chr7:123706066-123746894 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033367
protein coding gene Chr7:112459244-112498878 (+)
PWK/PhJ MGP_PWKPhJ_G0031585
protein coding gene Chr7:101587124-101630738 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031433
protein coding gene Chr7:99163209-99200199 (+)
WSB/EiJ MGP_WSBEiJ_G0031991
protein coding gene Chr7:113313184-113351349 (+)



Homology
more
  • Human Ortholog
    IPO7, importin 7
  • Vertebrate Orthologs
    9
  • Human Ortholog
    IPO7, importin 7
    Orthology source: HomoloGene, HGNC
  • Synonyms
    Imp7, RANBP7
  • Links
    NCBI Gene ID: 10527
    neXtProt AC: NX_O95373
    UniProt: O95373

  • Chr Location
    11p15.4; chr11:9384622-9448127 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 4659
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: IPO7
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 233726 NCBI Gene Model | MGI Sequence Detail 38295 C57BL/6J ±  kb
    transcript NM_181517 RefSeq | MGI Sequence Detail 4722 C57BL/6  
    polypeptide Q9EPL8 UniProt | EBI | MGI Sequence Detail 1038 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 20
      Genomic 1
      cDNA 19

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2442438
    References
    more
    • Summaries
      All 49
      Developmental Gene Expression 1
      Gene Ontology 8
      Phenotypes 17
    • Earliest
      J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
    • Latest
      J:193640 Lo JC, et al., RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly. PLoS Genet. 2012;8(10):e1002969

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    10/13/2020
    MGI 6.16
    The Jackson Laboratory