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Adam20 Gene Detail
Summary
  • Symbol
    Adam20
  • Name
    a disintegrin and metallopeptidase domain 20
  • Synonyms
    4930529F22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2152342
    NCBI Gene: 384806
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:40793273-40797303 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 23.89 cM, cytoband B1.2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    45 from dbSNP Build 142
  • Strain Annotations
    6
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2152342
protein coding gene Chr8:40793273-40797342 (+)
129S1/SvImJ no annotation
A/J MGP_AJ_G0033537
protein coding gene Chr8:38118683-38122030 (+)
AKR/J MGP_AKRJ_G0033462
protein coding gene Chr8:39228182-39287587 (+)
BALB/cJ MGP_BALBcJ_G0033533
protein coding gene Chr8:38212693-38259866 (+)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0034050
protein coding gene Chr8:41120747-41137802 (+)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0034068
protein coding gene Chr8:39407207-39414515 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    ADAM20, ADAM metallopeptidase domain 20
  • Vertebrate Orthologs
    7
  • Human Ortholog
    ADAM20, ADAM metallopeptidase domain 20
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 8748
    neXtProt AC: NX_O43506
    UniProt: O43506

  • Chr Location
    14q24.2; chr14:70520817-70564742 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000046282 Ensembl Gene Model | MGI Sequence Detail 4031 C57BL/6J ±  kb
transcript ENSMUST00000056331 Ensembl | MGI Sequence Detail 2589 Not Applicable  
polypeptide ENSMUSP00000057794 Ensembl | MGI Sequence Detail 760 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 1
References
more
  • Summaries
    All 20
    Developmental Gene Expression 1
    Phenotypes 4
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:273907 Nandadasa S, et al., Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis. Nat Commun. 2019 Feb 27;10(1):953

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/23/2020
MGI 6.15
The Jackson Laboratory