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Mta3
Gene Detail
Symbol

Name
ID
Mta3
metastasis associated 3
MGI:2151172
Synonyms
1110002J22Rik, mKIAA1266
Feature Type
protein coding gene
Genetic Map
Chromosome 17
54.53 cM, cytoband E4
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr17:83706163-83821516 bp, + strand
From VEGA annotation of GRCm38

  115354 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:14282  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: MTA3
Gene Tree: Mta3

Human
homologs
MTA3, metastasis associated 1 family, member 3
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 57504
neXtProt AC: NX_Q9BTC8

Human Chr (Location): 2p21; chr2:42494569-42795030 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(277) : Gene trapped(273) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Mta3 interacts with 362 markers (Mir1a-1, Mir1a-2, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process negative regulation of transcription, DNA-templated, positive regulation of cell proliferation, ...
Component cohesin complex, cytoplasm, ...
Function chromatin binding, DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (59)    Tissues (59)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 51
RT-PCR 8
cDNA source data(19)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA MTA3 ZFIN mta3    NEW 
Molecular
reagents
All nucleic(20) cDNA(19) Primer pair(1)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000017301 (Evidence)
Ensembl Gene Model ENSMUSG00000055817 (Evidence)
Entrez Gene 116871 (Evidence)
DFCI TC1630863, TC1577269, TC1603961, TC1591315
DoTS DT.91310764, DT.87045288, DT.101344163, DT.526667, DT.101371579, DT.91565715, DT.97415222
NIA Mouse Gene Index U043626
PDB 2CRG
Consensus CDS Project CCDS28997.1, CCDS50195.1, CCDS50196.1, CCDS50197.1
International Mouse Phenotyping Consortium Status Mta3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017301 VEGA Gene Model | MGI Sequence Detail 115354 C57BL/6J ±  kb
transcript OTTMUST00000041971 VEGA | MGI Sequence Detail 2087 Not Applicable 
polypeptide OTTMUSP00000018873 VEGA | MGI Sequence Detail 591 Not Applicable 

For the selected sequences
All sequences(105) RefSeq(24) UniProt(12)
Polymorphisms
SNPs within 2kb(1155 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001025 Bromo adjacent homology (BAH) domain
InterPro IPR000949 ELM2 domain
InterPro IPR009057 Homeodomain-like
InterPro IPR017884 SANT domain
InterPro IPR001005 SANT/Myb domain
InterPro IPR000679 Zinc finger, GATA-type
Protein Ontology PR:000010709 metastasis-associated protein MTA3
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:194303 D R D, et al., Mi-2/NuRD is required in renal progenitor cells during embryonic kidney development. Dev Biol. 2013 Mar 15;375(2):105-16
All references(45)
Other
accession IDs
MGI:1915798

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory