Mta3
Gene Detail

Symbol

Name
ID

Mta3
metastasis associated 3
MGI:2151172

Synonyms

1110002J22Rik, mKIAA1266

Feature Type

protein coding gene

Genetic Map

Chromosome 17
54.53 cM, cytoband E4
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr17:83706163-83821516 bp, + strand From VEGA annotation of GRCm38   115354 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

HomoloGene:14282  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Mta3

Human
homologs

Human Homolog		MTA3, metastasis associated 1 family, member 3
NCBI Gene ID		57504
neXtProt AC		NX_Q9BTC8
Human Chr (Location)		2p21; chr2:42494569-42756947 (+)  GRCh38

Mutations,
alleles, and
phenotypes

All mutations/alleles(277) : Gene trapped(273) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )

Interactions

Mta3 interacts with 363 markers (Mir1a-1, Mir1a-2, Mir9-1, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (20 annotations)

Process	positive regulation of cell proliferation, positive regulation of G2/M transition of mitotic cell cycle, ...
Component	cohesin complex, cytoplasm, ...
Function	chromatin binding, DNA binding, ...

External Resources: FuncBase

Expression

Literature Summary: (7 records)

Data Summary: Results (59)    Tissues (59)    Images (3)    Tissue x Stage Matrix (view)

Assay Type	Results
RNA in situ	51
RT-PCR	8

cDNA source data(18)
External Resources: Allen Institute   GEO   Expression Atlas

Molecular
reagents

All nucleic(19) cDNA(18) Primer pair(1)
Microarray probesets(6)

Other database
links

VEGA Gene Model	OTTMUSG00000017301 (Evidence)
Ensembl Gene Model	ENSMUSG00000055817 (Evidence)
Entrez Gene	116871 (Evidence)
DFCI	TC1577269, TC1603961, TC1591315, TC1630863
DoTS	DT.91310764, DT.91565715, DT.87045288, DT.526667, DT.101344163, DT.101371579, DT.97415222
NIA Mouse Gene Index	U043626
PDB	2CRG
Consensus CDS Project	CCDS28997.1, CCDS50195.1, CCDS50196.1, CCDS50197.1
International Mouse Knockout Project Status	Mta3

Sequences

Length	Strain/Species
genomic	OTTMUSG00000017301	VEGA Gene Model | MGI Sequence Detail	115354	C57BL/6J
transcript	OTTMUST00000041971	VEGA | MGI Sequence Detail	2087	Not Applicable
polypeptide	OTTMUSP00000018873	VEGA | MGI Sequence Detail	591	Not Applicable

All sequences(100) RefSeq(20) UniProt(12)

Polymorphisms

SNPs within 2kb(1155 from dbSNP Build 137)

Protein-related
information

Resource	ID	Description
InterPro	IPR001025	Bromo adjacent homology (BAH) domain
InterPro	IPR000949	ELM2 domain
InterPro	IPR009057	Homeodomain-like
InterPro	IPR017884	SANT domain
InterPro	IPR001005	SANT/Myb domain
InterPro	IPR000679	Zinc finger, GATA-type
Protein Ontology	PR:000010709	metastasis-associated protein MTA3

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:194303 D R D, et al., Mi-2/NuRD is required in renal progenitor cells during embryonic kidney development. Dev Biol. 2013 Mar 15;375(2):105-16
All references(47)

Other
accession IDs

MGI:1915798