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Adarb2 Gene Detail
Summary
  • Symbol
    Adarb2
  • Name
    adenosine deaminase, RNA-specific, B2
  • Synonyms
    Adar3, RED2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2151118
    NCBI Gene: 94191
  • Gene Overview
    MyGene.info: ADARB2
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:8202866-8768747 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 3.48 cM, cytoband A1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    5798 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2151118
protein coding gene Chr13:8202430-8768762 (.)
129S1/SvImJ MGP_129S1SvImJ_G0020217
protein coding gene Chr13:4807253-5386487 (+)
A/J MGP_AJ_G0020173
protein coding gene Chr13:4823202-5382959 (+)
AKR/J MGP_AKRJ_G0020148
protein coding gene Chr13:4867152-5452463 (+)
BALB/cJ MGP_BALBcJ_G0020156
protein coding gene Chr13:4798714-5378415 (+)
C3H/HeJ MGP_C3HHeJ_G0019960
protein coding gene Chr13:4970170-5557816 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020603
protein coding gene Chr13:5078063-5677376 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018212
protein coding gene Chr13:4795780-5340522 (+)
CAST/EiJ MGP_CASTEiJ_G0019500
protein coding gene Chr13:4702456-5292528 (+)
CBA/J MGP_CBAJ_G0019927
protein coding gene Chr13:5216931-5855382 (+)
DBA/2J MGP_DBA2J_G0020044
protein coding gene Chr13:4667929-5224329 (+)
FVB/NJ MGP_FVBNJ_G0020029
protein coding gene Chr13:4529536-5081535 (+)
LP/J MGP_LPJ_G0020118
protein coding gene Chr13:4925086-5503052 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020065
protein coding gene Chr13:5548382-6161151 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020631
protein coding gene Chr13:4823203-5405616 (+)
PWK/PhJ MGP_PWKPhJ_G0019261
protein coding gene Chr13:4669184-5238132 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019068
protein coding gene Chr13:4841359-5441869 (+)
WSB/EiJ MGP_WSBEiJ_G0019558
protein coding gene Chr13:4745798-5314446 (+)



Homology
more
  • Human Ortholog
    ADARB2, adenosine deaminase, RNA specific B2 (inactive)
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ADARB2, adenosine deaminase, RNA specific B2 (inactive)
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ADAR3, RED2
  • Links
    NCBI Gene ID: 105
    neXtProt AC: NX_Q9NS39
    UniProt: Q9NS39

  • Chr Location
    10p15.3; chr10:1177313-1737476 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000052551 Ensembl Gene Model | MGI Sequence Detail 565882 C57BL/6J ±  kb
transcript ENSMUST00000064473 Ensembl | MGI Sequence Detail 6721 Not Applicable  
polypeptide ENSMUSP00000064775 Ensembl | MGI Sequence Detail 745 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 21
    cDNA 18
    Primer pair 3

    Microarray probesets 3
References
more
  • Summaries
    All 35
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:62936 Slavov D, et al., Comparative analysis of the RED1 and RED2 A-to-I RNA editing genes from mammals, pufferfish and zebrafish. Gene. 2000 May 30;250(1-2):41-51
  • Latest
    J:264218 Mladenova D, et al., Adar3 Is Involved in Learning and Memory in Mice. Front Neurosci. 2018;12:243

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory