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Adarb2
Gene Detail
 Symbol
Name
ID
Adarb2
adenosine deaminase, RNA-specific, B2
MGI:2151118
Synonyms Adar3, RED2
Feature Type protein coding gene
Genetic Map
Chromosome 13
3.48 cM, cytoband A1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr13:8202866-8768747 bp, + strand
From VEGA annotation of GRCm38

  565882 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10276  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: double-stranded RNA-specific adenosine deaminase
Gene Tree: Adarb2

Human
homologs
Human Homolog ADARB2, adenosine deaminase, RNA-specific, B2 (non-functional)
NCBI Gene ID 105
neXtProt AC  NX_Q9NS39
Human Synonyms  ADAR3, RED2
Human Chr (Location)  10p15.3; chr10:1177313-1737476 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(1) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Adarb2 interacts with 399 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process mRNA processing, RNA processing
Component nucleus
Function adenosine deaminase activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (369)    Tissues (141)    Images (49)
Theiler Stages: 21, 22, 23, 28
Assay TypeResults
RNA in situ 367
RT-PCR 2
cDNA source data(15)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(19) cDNA(17) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000023149 (Evidence)
Ensembl Gene ModelENSMUSG00000052551 (Evidence)
Entrez Gene94191 (Evidence)
UniGene425794
DFCITC1585004, TC1588350
DoTSDT.55127638, DT.94185604, DT.97407777
NIA Mouse Gene IndexU014525
EC3.5.-.-
Consensus CDS ProjectCCDS26231.1, CCDS70428.1
International Mouse Knockout Project StatusAdarb2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023149 VEGA Gene Model | MGI Sequence Detail 565882 C57BL/6J ±  kb
transcript OTTMUST00000055962 VEGA | MGI Sequence Detail 6721 Not Applicable 
polypeptide OTTMUSP00000026855 VEGA | MGI Sequence Detail 745 Not Applicable 

For the selected sequences
All sequences(51) RefSeq(8) UniProt(5)
Polymorphisms SNPs within 2kb(5816 from dbSNP Build 137)    SNPs within 2kb including multiple locations(5820)
Protein-related
information
ResourceIDDescription
InterPro IPR002466 Adenosine deaminase/editase
InterPro IPR014720 Double-stranded RNA-binding-like domain
Protein Ontology PR:000003747 double-stranded RNA-specific editase B2
References (Earliest) J:62936 Slavov D, et al., Comparative analysis of the RED1 and RED2 A-to-I RNA editing genes from mammals, pufferfish and zebrafish. Gene. 2000 May 30;250(1-2):41-51
(Latest) J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
All references(35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory