Adarb2
Gene Detail

Symbol Name ID

Adarb2 adenosine deaminase, RNA-specific, B2 MGI:2151118

Synonyms

Adar3, RED2

Feature Type

protein coding gene

Genetic Map

Chromosome 13

3.48 cM, cytoband A1
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr13:8202866-8768747 bp, + strand From VEGA annotation of GRCm38   565882 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:10276  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: double-stranded RNA-specific adenosine deaminase
Gene Tree: Adarb2

Human homologs

Human Homolog		ADARB2, adenosine deaminase, RNA-specific, B2
NCBI Gene ID		105
neXtProt AC		NX_Q9NS39
Human Synonyms		ADAR3, RED2
Human Chr (Location)		10p15.3; chr10:1223253-1779670 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(5) : Targeted(4) Gene trapped(1)

Gene Ontology (GO) classifications

All GO classifications: (11 annotations)

Process	mRNA processing, RNA processing
Component	cytoplasm, mitochondrion, ...
Function	adenosine deaminase activity, double-stranded RNA binding, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (369)    Tissues (141)    Images (49)
Theiler Stages: 21, 22, 23, 28

Assay Type	Results
RNA in situ	367
RT-PCR	2

cDNA source data(15)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(19) cDNA(17) Primer pair(2)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000023149 (Evidence)
Ensembl Gene Model	ENSMUSG00000052551 (Evidence)
Entrez Gene	94191 (Evidence)
UniGene	425794
DFCI	TC1585004, TC1588350
DoTS	DT.55127638, DT.94185604, DT.97407777
NIA Mouse Gene Index	U014525
EC	3.5.-.-
Consensus CDS Project	CCDS26231.1
International Mouse Knockout Project Status	Adarb2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000023149	VEGA Gene Model | MGI Sequence Detail	565882	C57BL/6J
transcript	OTTMUST00000055962	VEGA | MGI Sequence Detail	6721	Not Applicable
polypeptide	OTTMUSP00000026855	VEGA | MGI Sequence Detail	745	Not Applicable

All sequences(44) RefSeq(2) UniProt(5)

Polymorphisms

SNPs(2687 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR002466	Adenosine deaminase/editase
InterPro	IPR001159	Double-stranded RNA-binding
InterPro	IPR014720	Double-stranded RNA-binding-like
Protein Ontology	PR:000003747	double-stranded RNA-specific editase B2

References

(Earliest) J:62936 Slavov D, et al., Comparative analysis of the RED1 and RED2 A-to-I RNA editing genes from mammals, pufferfish and zebrafish. Gene. 2000 May 30;250(1-2):41-51
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(33)