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Prelp
Gene Detail
Symbol

Name
ID
Prelp
proline arginine-rich end leucine-rich repeat
MGI:2151110
Synonyms
7330409J17Rik, SLRR2A
Feature Type
protein coding gene
Genetic Map
Chromosome 1
58.02 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr1:133910304-133921414 bp, - strand
From VEGA annotation of GRCm38

  11111 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2041  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: PRELP
Protein SuperFamily: class II small leucine-rich proteoglycan
Gene Tree: Prelp

Human
homologs
PRELP, proline/arginine-rich end leucine-rich repeat protein
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 5549
neXtProt AC: NX_P51888

Human Synonyms: MST161, MSTP161, SLRR2A

Human Chr (Location): 1q32; chr1:203475755-203491352 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Prelp interacts with 312 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process cell aging
Component extracellular exosome, extracellular matrix, ...
Function extracellular matrix structural constituent, heparin binding
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (26)    Tissues (20)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 8
RNA in situ 5
Northern blot 12
Western blot 1
cDNA source data(62)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase prelp ; ZFIN prelp    NEW 
Molecular
reagents
All nucleic(65) Genomic(2) cDNA(63)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000026872 (Evidence)
Ensembl Gene Model ENSMUSG00000041577 (Evidence)
Entrez Gene 116847 (Evidence)
UniGene 214514
DFCI TC1575610
DoTS DT.50314974
NIA Mouse Gene Index U021780
Consensus CDS Project CCDS15300.1
International Mouse Phenotyping Consortium Status Prelp
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026872 VEGA Gene Model | MGI Sequence Detail 11111 C57BL/6J ±  kb
transcript OTTMUST00000066465 VEGA | MGI Sequence Detail 3615 Not Applicable 
polypeptide OTTMUSP00000033309 VEGA | MGI Sequence Detail 378 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(8) UniProt(3)
Polymorphisms
SNPs within 2kb(169 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001611 Leucine-rich repeat
InterPro IPR000372 Leucine-rich repeat-containing N-terminal
InterPro IPR027216 Prolargin
Protein Ontology PR:000013199 prolargin
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
All references(39)
Other
accession IDs
MGI:1925348

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory