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Strn3 Gene Detail
Summary
  • Symbol
    Strn3
  • Name
    striatin, calmodulin binding protein 3
  • Synonyms
    SG2NA
  • Feature Type
    protein coding gene
  • IDs
    MGI:2151064
    NCBI Gene: 94186
  • Gene Overview
    MyGene.info: STRN3
Location & Maps
more
  • Sequence Map
    Chr12:51608541-51691914 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      83374 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 22.11 cM, cytoband C1
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    STRN3, striatin 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    STRN3, striatin 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PPP2R6B, SG2NA
  • Links
    NCBI Gene ID: 29966
    neXtProt AC: NX_Q13033

  • Chr Location
    14q12; chr14:30893779-31026528 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    21
  • Chemically induced (other)
    1
  • Gene trapped
    17
  • Targeted
    3
  • Genomic Mutations
    1 involving Strn3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020954 Ensembl Gene Model | MGI Sequence Detail 83374 C57BL/6J ±  kb
transcript ENSMUST00000013130 Ensembl | MGI Sequence Detail 4164 Not Applicable  
polypeptide ENSMUSP00000013130 Ensembl | MGI Sequence Detail 796 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    395 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 2
References
more
  • Summaries
    All 28
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:220132 Tanti GK, et al., SG2NA recruits DJ-1 and Akt into the mitochondria and membrane to protect cells from oxidative damage. Free Radic Biol Med. 2014 Oct;75:1-13

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory