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Cnnm4 Gene Detail
Summary
  • Symbol
    Cnnm4
  • Name
    cyclin M4
  • Synonyms
    5430430O18Rik, Acdp4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2151060
    NCBI Gene: 94220
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:36471620-36508764 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 15.28 cM, cytoband B
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    204 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2151060
protein coding gene Chr1:36471597-36508776 (+)
129S1/SvImJ MGP_129S1SvImJ_G0015924
protein coding gene Chr1:35003492-35040614 (+)
A/J MGP_AJ_G0015908
protein coding gene Chr1:34069830-34107095 (+)
AKR/J MGP_AKRJ_G0015863
protein coding gene Chr1:34552342-34589465 (+)
BALB/cJ MGP_BALBcJ_G0015862
protein coding gene Chr1:33758590-33795792 (+)
C3H/HeJ MGP_C3HHeJ_G0015695
protein coding gene Chr1:34740318-34778719 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016315
protein coding gene Chr1:36594719-36631797 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014037
protein coding gene Chr1:31121043-31158769 (+)
CAST/EiJ MGP_CASTEiJ_G0015276
protein coding gene Chr1:34629864-34667881 (+)
CBA/J MGP_CBAJ_G0015667
protein coding gene Chr1:37545436-37582557 (+)
DBA/2J MGP_DBA2J_G0015768
protein coding gene Chr1:33404719-33442267 (+)
FVB/NJ MGP_FVBNJ_G0015770
protein coding gene Chr1:32923600-32961026 (+)
LP/J MGP_LPJ_G0015838
protein coding gene Chr1:35371645-35409234 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015790
protein coding gene Chr1:39773767-39810816 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016362
protein coding gene Chr1:34583210-34620366 (+)
PWK/PhJ MGP_PWKPhJ_G0015059
protein coding gene Chr1:33151381-33189765 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014841
protein coding gene Chr1:34532073-34569164 (+)
WSB/EiJ MGP_WSBEiJ_G0015338
protein coding gene Chr1:34533832-34571887 (+)



Homology
more
  • Human Ortholog
    CNNM4, cyclin and CBS domain divalent metal cation transport mediator 4
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CNNM4, cyclin and CBS domain divalent metal cation transport mediator 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ACDP4
  • Links
    NCBI Gene ID: 26504
    neXtProt AC: NX_Q6P4Q7
    UniProt: Q6P4Q7

  • Chr Location
    2q11.2; chr2:96760902-96811891 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygous mutants exhibit hypomagnesemia and defective amelogenesis.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037408 Ensembl Gene Model | MGI Sequence Detail 37145 C57BL/6J ±  kb
transcript ENSMUST00000153128 Ensembl | MGI Sequence Detail 4547 Not Applicable  
polypeptide ENSMUSP00000121317 Ensembl | MGI Sequence Detail 771 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 5
Other
Accession IDs
less
MGI:1921746
References
more
  • Summaries
    All 36
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:256712 Yu C, et al., Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse. Cell Res. 2016 Mar;26(3):275-87

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory