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Cnnm4
Gene Detail
Symbol

Name
ID
Cnnm4
cyclin M4
MGI:2151060
Synonyms
5430430O18Rik, Acdp4
Feature Type
protein coding gene
Genetic Map
Chromosome 1
15.28 cM, cytoband B
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr1:36471620-36508764 bp, + strand
From VEGA annotation of GRCm38

  37145 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:75662  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: CNNM4
Gene Tree: Cnnm4

Human
homologs
CNNM4, cyclin and CBS domain divalent metal cation transport mediator 4
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 26504
neXtProt AC: NX_Q6P4Q7

Human Synonyms: ACDP4

Human Chr (Location): 2q11; chr2:96760902-96811891 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human CNNM4

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(1) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutants exhibit hypomagnesemia and defective amelogenesis.
 
Interactions
Cnnm4 interacts with 291 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
cDNA source data(5)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase cnnm4    NEW 
Molecular
reagents
All nucleic(5) cDNA(5)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000033420 (Evidence)
Ensembl Gene Model ENSMUSG00000037408 (Evidence)
Entrez Gene 94220 (Evidence)
DFCI TC1592148, TC1598189, TC1676079
DoTS DT.91405405, DT.527694, DT.103551612
NIA Mouse Gene Index U000159
Consensus CDS Project CCDS14879.2
International Mouse Phenotyping Consortium Status Cnnm4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033420 VEGA Gene Model | MGI Sequence Detail 37145 C57BL/6J ±  kb
transcript OTTMUST00000083926 VEGA | MGI Sequence Detail 4547 Not Applicable 
polypeptide OTTMUSP00000045156 VEGA | MGI Sequence Detail 771 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(205 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR018490 Cyclic nucleotide-binding-like
InterPro IPR000644 Cystathionine beta-synthase, core
InterPro IPR002550 Domain of unknown function DUF21
InterPro IPR014710 RmlC-like jelly roll fold
Protein Ontology PR:000005646 metal transporter CNNM4
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:219414 Funato Y, et al., Membrane protein CNNM4-dependent Mg2+ efflux suppresses tumor progression. J Clin Invest. 2014 Dec;124(12):5398-410
All references(32)
Other
accession IDs
MGI:1921746

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory