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Serpinb7
Gene Detail
 Symbol
Name
ID
Serpinb7
serine (or cysteine) peptidase inhibitor, clade B, member 7
MGI:2151053
Synonyms 4631416M05Rik, megsin, ovalbumin
Feature Type protein coding gene
Genetic Map
Chromosome 1
50.34 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr1:107399655-107452689 bp, + strand
From VEGA annotation of GRCm38

  53035 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68363  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: serpin
Gene Tree: Serpinb7

Human
homologs
Human Homolog SERPINB7, serpin peptidase inhibitor, clade B (ovalbumin), member 7
NCBI Gene ID 8710
neXtProt AC  NX_O75635
Human Synonyms  MEGSIN, PPKN, TP55
Human Chr (Location)  18q21.33; chr18:63753047-63805376 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human SERPINB7
Mutations,
alleles, and
phenotypes
Incidental mutations (data from Mutagenetix , APF )
Interactions
Serpinb7 interacts with 142 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process negative regulation of endopeptidase activity, negative regulation of peptidase activity, ...
Component cytoplasm, extracellular space
Function peptidase inhibitor activity, serine-type endopeptidase inhibitor activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (1)    Tissues (1)    Images (1)
Theiler Stages: 23
Assay TypeResults
RNA in situ 1
cDNA source data(3)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(6) Genomic(3) cDNA(3)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000021004 (Evidence)
Ensembl Gene ModelENSMUSG00000067001 (Evidence)
Entrez Gene116872 (Evidence)
UniGene66015
DFCITC1588831
DoTSDT.101324599
NIA Mouse Gene IndexU000688
Consensus CDS ProjectCCDS35686.1
International Mouse Knockout Project StatusSerpinb7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021004 VEGA Gene Model | MGI Sequence Detail 53035 C57BL/6J ±  kb
transcript OTTMUST00000049656 VEGA | MGI Sequence Detail 1869 Not Applicable 
polypeptide OTTMUSP00000023042 VEGA | MGI Sequence Detail 380 Not Applicable 

For the selected sequences
All sequences(28) RefSeq(6) UniProt(3)
Polymorphisms SNPs within 2kb(466 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023795 Protease inhibitor I4, serpin, conserved site
InterPro IPR023796 Serpin domain
InterPro IPR000215 Serpin family
Protein Ontology PR:000014698 serpin B7
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(30)
Other
accession IDs
MGI:1918031

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory