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Lsm10
Gene Detail
Symbol

Name
ID
Lsm10
U7 snRNP-specific Sm-like protein LSM10
MGI:2151045
Feature Type
protein coding gene
Genetic Map
Chromosome 4
59.88 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr4:126096623-126098584 bp, + strand
From VEGA annotation of GRCm38

  1962 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:13154  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Gene Tree: Lsm10

Human
homologs
Human Homolog LSM10, LSM10, U7 small nuclear RNA associated
NCBI Gene ID 84967
neXtProt AC  NX_Q969L4
Human Synonyms  MST074, MSTP074
Human Chr (Location)  1p34.3; chr1:36393430-36397892 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(6) Targeted(3)
Interactions
Lsm10 interacts with 39 markers (Mir7-1, Mir15a, Mir24-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process mRNA processing, positive regulation of G1/S transition of mitotic cell cycle, ...
Component Cajal body, nucleoplasm, ...
Function histone pre-mRNA DCP binding, RNA binding, ...
External Resources: FuncBase
Expression
cDNA source data(49)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(49) cDNA(49)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000009295 (Evidence)
Ensembl Gene ModelENSMUSG00000050188 (Evidence)
Entrez Gene116748 (Evidence)
UniGene41865
DFCITC1578865
DoTSDT.533952
NIA Mouse Gene IndexU004810
Consensus CDS ProjectCCDS18642.1
International Mouse Knockout Project StatusLsm10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009295 VEGA Gene Model | MGI Sequence Detail 1962 C57BL/6J ±  kb
transcript OTTMUST00000021094 VEGA | MGI Sequence Detail 943 Not Applicable 
polypeptide OTTMUSP00000009664 VEGA | MGI Sequence Detail 122 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(8) UniProt(5)
Polymorphisms
SNPs within 2kb(38 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR010920 Like-Sm (LSM) domain
InterPro IPR001163 Ribonucleoprotein LSM domain
InterPro IPR006649 Ribonucleoprotein LSM domain, eukaryotic/archaea-type
Protein Ontology PR:000009955 U7 snRNA-associated Sm-like protein LSm10
References
(Earliest) J:71849 Pillai RS, et al., Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein. EMBO J. 2001 Oct 1;20(19):5470-9
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(34)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory