About   Help   FAQ
Lsm10 Gene Detail
Summary
  • Symbol
    Lsm10
  • Name
    U7 snRNP-specific Sm-like protein LSM10
  • Feature Type
    protein coding gene
  • IDs
    MGI:2151045
    NCBI Gene: 116748
Location & Maps
more
  • Sequence Map
    Chr4:126096623-126098584 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      1962 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    LSM10, LSM10, U7 small nuclear RNA associated
  • Vertebrate Orthologs
    11
  • Human Ortholog
    LSM10, LSM10, U7 small nuclear RNA associated
    Orthology source: HGNC, HomoloGene
  • Synonyms
    MST074, MSTP074
  • Links
    NCBI Gene ID: 84967
    neXtProt AC: NX_Q969L4

  • Chr Location
    1p34.3; chr1:36393420-36397959 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 13154
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;2 zebrafish
  • HCOP
    human homology predictions: LSM10
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    13
  • Chemically induced (other)
    2
  • Gene trapped
    6
  • Radiation induced
    1
  • Targeted
    4
  • Genomic Mutations
    4 involving Lsm10
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009295 VEGA Gene Model | MGI Sequence Detail 1962 C57BL/6J ±  kb
transcript OTTMUST00000021094 VEGA | MGI Sequence Detail 943 Not Applicable  
polypeptide OTTMUSP00000009664 VEGA | MGI Sequence Detail 122 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    38 from dbSNP Build 137
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000009955 U7 snRNA-associated Sm-like protein LSm10
  • InterPro Domains
    IPR010920 LSM domain
    IPR001163 LSM domain, eukaryotic/archaea-type
Molecular
Reagents
less
  • All nucleic 49
    cDNA 49

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Gene Ontology 4
    Phenotypes 13
  • Earliest
    J:71849 Pillai RS, et al., Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein. EMBO J. 2001 Oct 1;20(19):5470-9
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/02/2016
MGI 6.02
The Jackson Laboratory