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Lsm10 Gene Detail
Summary
  • Symbol
    Lsm10
  • Name
    U7 snRNP-specific Sm-like protein LSM10
  • Feature Type
    protein coding gene
  • IDs
    MGI:2151045
    NCBI Gene: 116748
  • Gene Overview
    MyGene.info: LSM10
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:126096623-126098584 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 59.88 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    38 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2151045
protein coding gene Chr4:126096577-126098584 (.)
129S1/SvImJ MGP_129S1SvImJ_G0028770
protein coding gene Chr4:127749790-127751751 (+)
A/J MGP_AJ_G0028729
protein coding gene Chr4:122713371-122715332 (+)
AKR/J MGP_AKRJ_G0028682
protein coding gene Chr4:126099685-126101646 (+)
BALB/cJ MGP_BALBcJ_G0028752
protein coding gene Chr4:123298630-123300590 (+)
C3H/HeJ MGP_C3HHeJ_G0028466
protein coding gene Chr4:126147552-126149512 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029194
protein coding gene Chr4:132628847-132630808 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026467
protein coding gene Chr4:115869992-115871967 (+)
CAST/EiJ MGP_CASTEiJ_G0027899
protein coding gene Chr4:124266410-124268349 (+)
CBA/J MGP_CBAJ_G0028432
protein coding gene Chr4:135845281-135847241 (+)
DBA/2J MGP_DBA2J_G0028581
protein coding gene Chr4:123181582-123183542 (+)
FVB/NJ MGP_FVBNJ_G0028548
protein coding gene Chr4:121830182-121832142 (+)
LP/J MGP_LPJ_G0028682
protein coding gene Chr4:128036713-128038674 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028574
protein coding gene Chr4:140874437-140876397 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029232
protein coding gene Chr4:126445669-126447630 (+)
PWK/PhJ MGP_PWKPhJ_G0027620
protein coding gene Chr4:119642470-119644432 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027446
protein coding gene Chr4:122261759-122263732 (+)
WSB/EiJ MGP_WSBEiJ_G0027979
protein coding gene Chr4:126537199-126539160 (+)



Homology
more
  • Human Ortholog
    LSM10, LSM10, U7 small nuclear RNA associated
  • Vertebrate Orthologs
    11
  • Human Ortholog
    LSM10, LSM10, U7 small nuclear RNA associated
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MST074, MSTP074
  • Links
    NCBI Gene ID: 84967
    neXtProt AC: NX_Q969L4
    UniProt: Q969L4

  • Chr Location
    1p34.3; chr1:36393420-36397959 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 13154
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;2 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: LSM10
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
  • All Mutations and Alleles
    13
  • Chemically induced (other)
    2
  • Gene trapped
    6
  • Radiation induced
    1
  • Targeted
    4
  • Genomic Mutations
    4 involving Lsm10
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000050188 Ensembl Gene Model | MGI Sequence Detail 1962 C57BL/6J ±  kb
transcript ENSMUST00000179323 Ensembl | MGI Sequence Detail 808 Not Applicable  
polypeptide ENSMUSP00000136585 Ensembl | MGI Sequence Detail 122 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 50
    cDNA 50

    Microarray probesets 3
References
more
  • Summaries
    All 36
    Gene Ontology 4
    Phenotypes 13
  • Earliest
    J:71849 Pillai RS, et al., Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein. EMBO J. 2001 Oct 1;20(19):5470-9
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory