Defb6
Gene Detail

Symbol Name ID

Defb6 defensin beta 6 MGI:2151044

Synonyms

mBD-6

Feature Type

protein coding gene

Genetic Map

Chromosome 8

10.35 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr8:19225478-19228209 bp, + strand From VEGA annotation of GRCm38   2732 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

Protein SuperFamily: crotamine
Gene Tree: Defb6

Gene Ontology (GO) classifications

All GO classifications: (6 annotations)

Process	defense response, defense response to bacterium, ...
Component	extracellular region

External Resources: FuncBase

Expression

Literature Summary: (1 records)
cDNA source data(4)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(5) Genomic(1) cDNA(4)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000020598 (Evidence)
Ensembl Gene Model	ENSMUSG00000050756 (Evidence)
Entrez Gene	116746 (Evidence)
UniGene	358822
DFCI	TC1594570
DoTS	DT.94261772
Consensus CDS Project	CCDS40255.1
International Mouse Knockout Project Status	Defb6

Sequences

Length	Strain/Species
genomic	OTTMUSG00000020598	VEGA Gene Model | MGI Sequence Detail	2732	C57BL/6J
transcript	OTTMUST00000048802	VEGA | MGI Sequence Detail	323	Not Applicable
polypeptide	OTTMUSP00000022476	VEGA | MGI Sequence Detail	63	Not Applicable

All sequences(19) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(4 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001855	Beta defensin type
Protein Ontology	PR:000006820	beta-defensin 6

References

(Earliest) J:71039 Yamaguchi Y, et al., A novel mouse beta-defensin, mBD-6, predominantly expressed in skeletal muscle. J Biol Chem. 2001 Aug 24;276(34):31510-4
(Latest) J:148089 Taylor K, et al., Defensin-related peptide 1 (Defr1) is allelic to Defb8 and chemoattracts immature DC and CD4+ T cells independently of CCR6. Eur J Immunol. 2009 May;39(5):1353-60
All references(22)