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Defb6
Gene Detail
 Symbol
Name
ID
Defb6
defensin beta 6
MGI:2151044
Synonyms mBD-6
Feature Type protein coding gene
Genetic Map
Chromosome 8
10.35 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:19225478-19228209 bp, + strand
From VEGA annotation of GRCm38

  2732 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Protein SuperFamily: crotamine
Gene Tree: Defb6
Interactions
Defb6 interacts with 28 markers (Mir23a, Mir23b, Mir33, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process defense response, defense response to bacterium, ...
Component extracellular region
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(4)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(5) Genomic(1) cDNA(4)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000020598 (Evidence)
Ensembl Gene ModelENSMUSG00000050756 (Evidence)
Entrez Gene116746 (Evidence)
UniGene358822
DFCITC1594570
DoTSDT.94261772
Consensus CDS ProjectCCDS40255.1
International Mouse Knockout Project StatusDefb6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020598 VEGA Gene Model | MGI Sequence Detail 2732 C57BL/6J ±  kb
transcript OTTMUST00000048802 VEGA | MGI Sequence Detail 323 Not Applicable 
polypeptide OTTMUSP00000022476 VEGA | MGI Sequence Detail 63 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(11 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001855 Beta defensin type
Protein Ontology PR:000006820 beta-defensin 6
References (Earliest) J:71039 Yamaguchi Y, et al., A novel mouse beta-defensin, mBD-6, predominantly expressed in skeletal muscle. J Biol Chem. 2001 Aug 24;276(34):31510-4
(Latest) J:148089 Taylor K, et al., Defensin-related peptide 1 (Defr1) is allelic to Defb8 and chemoattracts immature DC and CD4+ T cells independently of CCR6. Eur J Immunol. 2009 May;39(5):1353-60
All references(22)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory