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Prss28
Gene Detail
 Symbol
Name
ID
Prss28
protease, serine 28
MGI:2149951
Synonyms Isp1, mIsp-1
Feature Type protein coding gene
Genetic Map
Chromosome 17
12.53 cM, cytoband A3.3
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr17:25308646-25311876 bp, + strand
From VEGA annotation of GRCm38

  3231 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:130906  Vertebrate Homology Class
1 mouse; 1 rat; 1 rhesus macaque

Protein SuperFamily: trypsin
Gene Tree: Prss28

Alleles
and
phenotypes
All alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process embryo implantation, proteolysis
Component extracellular region
Function catalytic activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (32)    Tissues (23)    Images (8)
Theiler Stages: 10, 11, 18, 23, 25, 28
Assay TypeResults
RNA in situ 10
RT-PCR 22
cDNA source data(4)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(6) cDNA(4) Primer pair(2)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000033715 (Evidence)
Ensembl Gene ModelENSMUSG00000024171 (Evidence)
Entrez Gene114661 (Evidence)
UniGene207081
DFCITC1601124
DoTSDT.87042764
NIA Mouse Gene IndexU017671
EC3.4.21.-
Consensus CDS ProjectCCDS28515.1
International Mouse Knockout Project StatusPrss28
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033715 VEGA Gene Model | MGI Sequence Detail 3231 C57BL/6J ±  kb
transcript OTTMUST00000084923 VEGA | MGI Sequence Detail 1190 Not Applicable 
polypeptide OTTMUSP00000045810 VEGA | MGI Sequence Detail 274 Not Applicable 

For the selected sequences
All sequences(17) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(136 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000013556 serine protease 28
References (Earliest) J:71427 O'Sullivan CM, et al., A novel murine tryptase involved in blastocyst hatching and outgrowth. Reproduction. 2001 Jul;122(1):61-71
(Latest) J:176496 Khalife M, et al., Transcriptomic analysis brings new insight into the biological role of the prion protein during mouse embryogenesis. PLoS One. 2011;6(8):e23253
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory