Prss28
Gene Detail

Symbol Name ID

Prss28 protease, serine, 28 MGI:2149951

Synonyms

Isp1, mIsp-1

Feature Type

protein coding gene

Genetic Map

Chromosome 17

12.53 cM, cytoband A3.3
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr17:25308646-25311876 bp, + strand From VEGA annotation of GRCm38   3231 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:130906  Vertebrate Homology Class
1 mouse; 1 rhesus macaque

Protein SuperFamily: trypsin
Gene Tree: Prss28

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (10 annotations)

Process	embryo implantation, metabolic process, ...
Component	extracellular region
Function	catalytic activity, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (5 records)
Data Summary: Results (32)    Tissues (23)    Images (8)
Theiler Stages: 10, 11, 18, 23, 25, 28

Assay Type	Results
RNA in situ	10
RT-PCR	22

cDNA source data(4)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(6) cDNA(4) Primer pair(2)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000033715 (Evidence)
Ensembl Gene Model	ENSMUSG00000024171 (Evidence)
Entrez Gene	114661 (Evidence)
UniGene	207081
DFCI	TC1601124
DoTS	DT.87042764
NIA Mouse Gene Index	U017671
EC	3.4.21.-
Consensus CDS Project	CCDS28515.1
International Mouse Knockout Project Status	Prss28

Sequences

Length	Strain/Species
genomic	OTTMUSG00000033715	VEGA Gene Model | MGI Sequence Detail	3231	C57BL/6J
transcript	OTTMUST00000084923	VEGA | MGI Sequence Detail	1190	Not Applicable
polypeptide	OTTMUSP00000045810	VEGA | MGI Sequence Detail	274	Not Applicable

All sequences(17) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(120 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR009003	Peptidase cysteine/serine, trypsin-like
InterPro	IPR001314	Peptidase S1A, chymotrypsin-type
InterPro	IPR001254	Peptidase S1/S6, chymotrypsin/Hap
InterPro	IPR018114	Peptidase S1/S6, chymotrypsin/Hap, active site
Protein Ontology	PR:000013556	serine protease 28

References

(Earliest) J:71427 O'Sullivan CM, et al., A novel murine tryptase involved in blastocyst hatching and outgrowth. Reproduction. 2001 Jul;122(1):61-71
(Latest) J:176496 Khalife M, et al., Transcriptomic analysis brings new insight into the biological role of the prion protein during mouse embryogenesis. PLoS One. 2011;6(8):e23253
All references(28)