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Greb1 Gene Detail
Summary
  • Symbol
    Greb1
  • Name
    gene regulated by estrogen in breast cancer protein
  • Synonyms
    5730583K22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2149712
    NCBI Gene: 268527
Location & Maps
more
  • Sequence Map
    Chr12:16670615-16800886 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      130272 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    GREB1, growth regulation by estrogen in breast cancer 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GREB1, growth regulation by estrogen in breast cancer 1
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 9687
    neXtProt AC: NX_Q4ZG55

  • Chr Location
    2p25.1; chr2:11534116-11642788 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 8780
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: GREB1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000032970 VEGA Gene Model | MGI Sequence Detail 130272 C57BL/6J ±  kb
transcript OTTMUST00000082200 VEGA | MGI Sequence Detail 8058 Not Applicable  
polypeptide OTTMUSP00000044039 VEGA | MGI Sequence Detail 1954 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1818 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 17
    Other 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:1354180, MGI:2144961
References
more
  • Summaries
    All 32
    Developmental Gene Expression 6
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:60252 Peterfy M, et al., Genetic, physical, and transcript map of the fld region on mouse chromosome 12. Genomics. 1999 Dec 15;62(3):436-44
  • Latest
    J:174459 Boyle MP, et al., Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala. J Comp Neurol. 2011 Aug 1;519(11):2061-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory