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Greb1 Gene Detail
Summary
  • Symbol
    Greb1
  • Name
    gene regulated by estrogen in breast cancer protein
  • Synonyms
    5730583K22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2149712
    NCBI Gene: 268527
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr12:16670615-16800886 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      130272 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 8.00 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    GREB1, growth regulating estrogen receptor binding 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GREB1, growth regulating estrogen receptor binding 1
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 9687
    neXtProt AC: NX_Q4ZG55
    UniProt: Q4ZG55

  • Chr Location
    2p25.1; chr2:11534116-11642788 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 8780
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: GREB1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000032970 VEGA Gene Model | MGI Sequence Detail 130272 C57BL/6J ±  kb
    transcript OTTMUST00000082200 VEGA | MGI Sequence Detail 8058 Not Applicable  
    polypeptide OTTMUSP00000044039 VEGA | MGI Sequence Detail 1954 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      1818 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 19
      cDNA 18
      Primer pair 1

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:1354180, MGI:2144961
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 8
      Gene Ontology 1
      Phenotypes 5
    • Earliest
      J:60252 Peterfy M, et al., Genetic, physical, and transcript map of the fld region on mouse chromosome 12. Genomics. 1999 Dec 15;62(3):436-44
    • Latest
      J:259848 Chal J, et al., Recapitulating early development of mouse musculoskeletal precursors of the paraxial mesoderm in vitro. Development. 2018 Mar 19;145(6):None

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    05/15/2018
    MGI 6.12
    The Jackson Laboratory