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Slc13a3 Gene Detail
Summary
  • Symbol
    Slc13a3
  • Name
    solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
  • Synonyms
    NaDC3, NaDC-3, SDCT2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2149635
    NCBI Gene: 114644
  • Gene Overview
    MyGene.info: SLC13A3
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:165405295-165473197 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 85.54 cM, cytoband H3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    532 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2149635
protein coding gene Chr2:165405028-165473230 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026894
protein coding gene Chr2:170968381-171040775 (-)
A/J MGP_AJ_G0026861
protein coding gene Chr2:163960048-164032492 (-)
AKR/J MGP_AKRJ_G0026832
protein coding gene Chr2:168848447-168919616 (-)
BALB/cJ MGP_BALBcJ_G0026870
protein coding gene Chr2:164320348-164388717 (-)
C3H/HeJ MGP_C3HHeJ_G0026612
protein coding gene Chr2:169197691-169268993 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027317
protein coding gene Chr2:175913744-175986879 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024688
protein coding gene Chr2:157360519-157431196 (-)
CAST/EiJ MGP_CASTEiJ_G0026070
protein coding gene Chr2:169628144-169699462 (-)
CBA/J MGP_CBAJ_G0026589
protein coding gene Chr2:182310386-182389512 (-)
DBA/2J MGP_DBA2J_G0026727
protein coding gene Chr2:163115031-163184505 (-)
FVB/NJ MGP_FVBNJ_G0026693
protein coding gene Chr2:161558949-161629996 (-)
LP/J MGP_LPJ_G0026829
protein coding gene Chr2:171012458-171082400 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026712
protein coding gene Chr2:185826603-185909872 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027374
protein coding gene Chr2:168739235-168811274 (-)
PWK/PhJ MGP_PWKPhJ_G0025807
protein coding gene Chr2:162729847-162798266 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025608
protein coding gene Chr2:167660141-167732273 (-)
WSB/EiJ MGP_WSBEiJ_G0026143
protein coding gene Chr2:169635385-169707475 (-)



Homology
more
  • Human Ortholog
    SLC13A3, solute carrier family 13 member 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SLC13A3, solute carrier family 13 member 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ARLIAK, NADC3, SDCT2
  • Links
    NCBI Gene ID: 64849
    neXtProt AC: NX_Q8WWT9
    UniProt: Q8WWT9

  • Chr Location
    20q13.12; chr20:46557823-46684485 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 114644 NCBI Gene Model | MGI Sequence Detail 67903 C57BL/6J ±  kb
    transcript NM_054055 RefSeq | MGI Sequence Detail 3224 C57BL/6  
    polypeptide Q91Y63 UniProt | EBI | MGI Sequence Detail 600 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 64
      cDNA 62
      Primer pair 1
      Other 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 6
      Gene Ontology 6
      Phenotypes 6
    • Earliest
      J:69262 Pajor AM, et al., Cloning and functional characterization of a high-affinity Na(+)/dicarboxylate cotransporter from mouse brain. Am J Physiol Cell Physiol. 2001 May;280(5):C1215-23
    • Latest
      J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    10/08/2019
    MGI 6.14
    The Jackson Laboratory