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Oas1c
Gene Detail
Symbol

Name
ID
Oas1c
2'-5' oligoadenylate synthetase 1C
MGI:2149633
Synonyms
Oasl5
Feature Type
protein coding gene
Genetic Map
Chromosome 5
60.64 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr5:120800194-120812514 bp, - strand
From VEGA annotation of GRCm38

  12321 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:110815  Vertebrate Homology Class
3 mouse

HCOP human homology predictions: OAS1
Protein SuperFamily: oligo(A) synthetase
Gene Tree: Oas1c

Human
homologs
OAS1, 2'-5'-oligoadenylate synthetase 1, 40/46kDa
Orthology source: HGNC

IDs:
NCBI Gene ID: 4938
neXtProt AC: NX_P00973

Human Synonyms: IFI-4, OIAS, OIASI

Human Chr (Location): 12q24.2; chr12:112906934-112932049 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human OAS1

Mutations,
alleles, and
phenotypes
Incidental mutations (data from Mutagenetix , APF )
Interactions
Oas1c interacts with 159 markers (Mir23b, Mir25, Mir26a-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process biological_process
Component cellular_component
Function double-stranded RNA binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(26)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(29) Genomic(3) cDNA(26)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000026817 (Evidence)
Ensembl Gene Model ENSMUSG00000001166 (Evidence)
Entrez Gene 114643 (Evidence)
UniGene 43230
DFCI TC1613277, TC1581191
DoTS DT.101716680, DT.496767
Consensus CDS Project CCDS19626.1
International Mouse Phenotyping Consortium Status Oas1c
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026817 VEGA Gene Model | MGI Sequence Detail 12321 C57BL/6J ±  kb
transcript OTTMUST00000066317 VEGA | MGI Sequence Detail 2291 Not Applicable 
polypeptide OTTMUSP00000033220 VEGA | MGI Sequence Detail 362 Not Applicable 

For the selected sequences
All sequences(45) RefSeq(6) UniProt(4)
Polymorphisms
SNPs within 2kb(2 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026774 2'-5'-oligoadenylate synthase
InterPro IPR018952 2'-5'-oligoadenylate synthetase 1, domain 2/C-terminal
InterPro IPR006116 2-5-oligoadenylate synthetase, N-terminal
References
(Earliest) J:70792 Shibata S, et al., Cloning of a novel 2',5'-oligoadenylate synthetase-like molecule, Oasl5 in mice. Gene. 2001 Jun 27;271(2):261-71
(Latest) J:192649 Kristiansen H, et al., The oligoadenylate synthetase family: an ancient protein family with multiple antiviral activities. J Interferon Cytokine Res. 2011 Jan;31(1):41-7
All references(24)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory