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Oas1c Gene Detail
Summary
  • Symbol
    Oas1c
  • Name
    2'-5' oligoadenylate synthetase 1C
  • Synonyms
    Oasl5
  • Feature Type
    protein coding gene
  • IDs
    MGI:2149633
    NCBI Gene: 114643
  • Gene Overview
    MyGene.info: OAS1
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:120800194-120812514 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 60.64 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2149633
protein coding gene Chr5:120800194-120812540 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030015
protein coding gene Chr5:124215438-124230523 (-)
A/J MGP_AJ_G0029980
protein coding gene Chr5:119050657-119062945 (-)
AKR/J MGP_AKRJ_G0029918
protein coding gene Chr5:122901428-122928253 (-)
BALB/cJ MGP_BALBcJ_G0029991
protein coding gene Chr5:120465649-120479004 (-)
C3H/HeJ MGP_C3HHeJ_G0029711
protein coding gene Chr5:123466383-123484192 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030446
protein coding gene Chr5:128870892-128885832 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027671
protein coding gene Chr5:113754824-113769215 (-)
CAST/EiJ MGP_CASTEiJ_G0029119
protein coding gene Chr5:122595758-122604002 (-)
CBA/J MGP_CBAJ_G0029679
protein coding gene Chr5:133905848-133927722 (-)
DBA/2J MGP_DBA2J_G0029829
protein coding gene Chr5:119151485-119167408 (-)
FVB/NJ MGP_FVBNJ_G0029784
protein coding gene Chr5:118097026-118104580 (-)
LP/J MGP_LPJ_G0029917
protein coding gene Chr5:124673583-124691015 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029815
protein coding gene Chr5:137837572-137866584 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030487
protein coding gene Chr5:122475254-122494409 (-)
PWK/PhJ MGP_PWKPhJ_G0028832
protein coding gene Chr5:117913324-117928872 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028671
protein coding gene Chr5:120145921-120155942 (-)
WSB/EiJ MGP_WSBEiJ_G0029194
protein coding gene Chr5:123072954-123082411 (-)



Homology
more
  • Human Ortholog
    OAS1, 2'-5'-oligoadenylate synthetase 1
  • Vertebrate Orthologs
    3
  • Human Ortholog
    OAS1, 2'-5'-oligoadenylate synthetase 1
    Orthology source: HGNC
  • Synonyms
    E18/E16, IFI-4, OIAS, OIASI
  • Links
    NCBI Gene ID: 4938
    neXtProt AC: NX_P00973
    UniProt: P00973

  • Chr Location
    12q24.13; chr12:112906777-112932190 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000001166 Ensembl Gene Model | MGI Sequence Detail 12321 C57BL/6J ±  kb
transcript ENSMUST00000117193 Ensembl | MGI Sequence Detail 2291 Not Applicable  
polypeptide ENSMUSP00000112584 Ensembl | MGI Sequence Detail 362 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • InterPro Domains
    IPR026774 2'-5'-oligoadenylate synthase
    IPR018952 2'-5'-oligoadenylate synthetase 1, domain 2/C-terminal
    IPR038121 2'-5'-oligoadenylate synthetase, domain 2 superfamily
    IPR006116 2-5-oligoadenylate synthetase, N-terminal
Molecular
Reagents
less
  • All nucleic 30
    Genomic 3
    cDNA 27

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/11/2019
MGI 6.14
The Jackson Laboratory