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Cygb
Gene Detail
 Symbol
Name
ID
Cygb
cytoglobin
MGI:2149481
Synonyms 3110001K20Rik, Staap
Feature Type protein coding gene
Genetic Map
Chromosome 11
81.45 cM, cytoband E2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:116645595-116654313 bp, - strand
From VEGA annotation of GRCm38

  8719 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12706  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: globin
Gene Tree: Cygb

Human
homologs
Human Homolog CYGB, cytoglobin
NCBI Gene ID 114757
neXtProt AC  NX_Q8WWM9
Human Synonyms  HGB, STAP
Human Chr (Location)  17q25; chr17:76527348-76537905 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(1) Targeted(4)
 
Mice homozygous or heterozygous for a null mutation display increased sensitivity to chemically induced tumors.
 
Interactions
Cygb interacts with 179 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process oxidation-reduction process, oxygen transport, ...
Component cytoplasm, neuronal cell body, ...
Function heme binding, iron ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (58)    Tissues (13)    Images (34)
Theiler Stages: 22, 23, 24, 26, 28
Assay TypeResults
RNA in situ 58
cDNA source data(48)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(49) cDNA(49)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000003946 (Evidence)
Ensembl Gene ModelENSMUSG00000020810 (Evidence)
Entrez Gene114886 (Evidence)
UniGene34598
DFCITC1579799, TC1596577
DoTSDT.101185500, DT.491437
NIA Mouse Gene IndexU033659
Consensus CDS ProjectCCDS25673.1
International Mouse Knockout Project StatusCygb
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003946 VEGA Gene Model | MGI Sequence Detail 8719 C57BL/6J ±  kb
transcript OTTMUST00000008757 VEGA | MGI Sequence Detail 2331 Not Applicable 
polypeptide OTTMUSP00000004268 VEGA | MGI Sequence Detail 190 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(2) UniProt(3)
Polymorphisms SNPs within 2kb(34 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000971 Globin
InterPro IPR013314 Globin, lamprey/hagfish type
InterPro IPR009050 Globin-like
InterPro IPR012292 Globin, structural domain
Protein Ontology PR:000006092 cytoglobin
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:206378 Singh S, et al., Cytoglobin modulates myogenic progenitor cell viability and muscle regeneration. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):E129-38
All references(42)
Other
accession IDs
MGI:1926136

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory