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Sec16b Gene Detail
Summary
  • Symbol
    Sec16b
  • Name
    SEC16 homolog B (S. cerevisiae)
  • Synonyms
    Lztr2, Rgpr, Rgpr-p117
  • Feature Type
    protein coding gene
  • IDs
    MGI:2148802
    NCBI Gene: 89867
  • Gene Overview
    MyGene.info: SEC16B
Location & Maps
more
  • Sequence Map
    Chr1:157506728-157568425 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      61698 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 68.00 cM, cytoband H1
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    SEC16B, SEC16 homolog B, endoplasmic reticulum export factor
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SEC16B, SEC16 homolog B, endoplasmic reticulum export factor
    Orthology source: HomoloGene, HGNC
  • Synonyms
    LZTR2, PGPR-p117, RGPR, SEC16S
  • Links
    NCBI Gene ID: 89866
    neXtProt AC: NX_Q96JE7

  • Chr Location
    1q25.2; chr1:177929107-177969915 (-)  GRCh38.p2
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    2
  • Targeted
    2
  • Genomic Mutations
    2 involving Sec16b
  • Incidental Mutations
    Mutagenetix , APF , CvDC
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    14
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    176
  • Tissues
    18
  • cDNA Data
    25
  • Literature Summary
    1
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022599 VEGA Gene Model | MGI Sequence Detail 61698 C57BL/6J ±  kb
transcript OTTMUST00000054130 VEGA | MGI Sequence Detail 4661 Not Applicable  
polypeptide OTTMUSP00000025792 VEGA | MGI Sequence Detail 1051 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    739 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000014582 protein transport protein Sec16B
  • InterPro Domains
    IPR024298 Ancestral coatomer element 1, Sec16/Sec31
    IPR024880 COPII coat assembly protein, Sec16
    IPR024340 Sec16, central conserved domain
Molecular
Reagents
less
  • All nucleic 25
    cDNA 25

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:71988 Misawa H, et al., Molecular cloning and sequencing of the cDNA coding for a novel regucalcin gene promoter region-related protein in rat, mouse and human liver. Int J Mol Med. 2001 Nov;8(5):513-20
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/27/2016
MGI 6.05 		The Jackson Laboratory