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Sec16b Gene Detail
Summary
  • Symbol
    Sec16b
  • Name
    SEC16 homolog B (S. cerevisiae)
  • Synonyms
    Lztr2, Rgpr, Rgpr-p117
  • Feature Type
    protein coding gene
  • IDs
    MGI:2148802
    NCBI Gene: 89867
  • Gene Overview
    MyGene.info: SEC16B
  • Alliance
    gene page
Location & Maps
more
  • Sequence Map
    Chr1:157506728-157568425 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      61698 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 68.00 cM, cytoband H1
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    SEC16B, SEC16 homolog B, endoplasmic reticulum export factor
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SEC16B, SEC16 homolog B, endoplasmic reticulum export factor
    Orthology source: HomoloGene, HGNC
  • Synonyms
    LZTR2, PGPR-p117, RGPR, RGPR-p117, SEC16S
  • Links
    NCBI Gene ID: 89866
    neXtProt AC: NX_Q96JE7
    UniProt: Q96JE7

  • Chr Location
    1q25.2; chr1:177929107-177969915 (-)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    176
  • Tissues
    18
  • cDNA Data
    25
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000022599 VEGA Gene Model | MGI Sequence Detail 61698 C57BL/6J ±  kb
    transcript OTTMUST00000054130 VEGA | MGI Sequence Detail 4661 Not Applicable  
    polypeptide OTTMUSP00000025792 VEGA | MGI Sequence Detail 1051 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      739 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 25
      cDNA 25

      Microarray probesets 2
    References
    more
    • Summaries
      All 26
      Developmental Gene Expression 1
      Gene Ontology 3
      Phenotypes 5
    • Earliest
      J:71988 Misawa H, et al., Molecular cloning and sequencing of the cDNA coding for a novel regucalcin gene promoter region-related protein in rat, mouse and human liver. Int J Mol Med. 2001 Nov;8(5):513-20
    • Latest
      J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    05/15/2018
    MGI 6.12     		The Jackson Laboratory