Sec16b
Gene Detail

Symbol Name ID

Sec16b SEC16 homolog B (S. cerevisiae) MGI:2148802

Synonyms

Lztr2, Rgpr, Rgpr-p117

Feature Type

protein coding gene

Genetic Map

Chromosome 1

68.00 cM, cytoband H1
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr1:157506728-157568425 bp, + strand From VEGA annotation of GRCm38   61698 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:13227  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Sec16b

Human homologs

Human Homolog		SEC16B, SEC16 homolog B (S. cerevisiae)
NCBI Gene ID		89866
neXtProt AC		NX_Q96JE7
Human Synonyms		LZTR2, PGPR-p117, RGPR, SEC16S
Human Chr (Location)		1q25.2; chr1:177929107-177969915 (-)  GRCh38

Mutations, alleles, and phenotypes

All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )

Interactions

Sec16b interacts with 223 markers (Mir1a-1, Mir1a-2, Mir1b, ...)

View All

Gene Ontology (GO) classifications

All GO classifications: (15 annotations)

Process	COPII vesicle coating, endoplasmic reticulum organization, ...
Component	endoplasmic reticulum, Golgi apparatus, ...
Function	molecular_function

External Resources: FuncBase

Expression

Literature Summary: (1 records)

Data Summary: Results (176)    Tissues (18)    Images (45)
Theiler Stages: 23

Assay Type	Results
RNA in situ	176

cDNA source data(25)
External Resources: Allen Institute   GEO   Expression Atlas

Molecular reagents

All nucleic(25) cDNA(25)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000022599 (Evidence)
Ensembl Gene Model	ENSMUSG00000026589 (Evidence)
Entrez Gene	89867 (Evidence)
UniGene	87114
DFCI	TC1583446, TC1701940
DoTS	DT.101725233, DT.110888875, DT.528598, DT.99839762
NIA Mouse Gene Index	U000965
Consensus CDS Project	CCDS15400.1
International Mouse Knockout Project Status	Sec16b

Sequences

Length	Strain/Species
genomic	OTTMUSG00000022599	VEGA Gene Model | MGI Sequence Detail	61698	C57BL/6J
transcript	OTTMUST00000054130	VEGA | MGI Sequence Detail	4664	Not Applicable
polypeptide	OTTMUSP00000025792	VEGA | MGI Sequence Detail	1051	Not Applicable

All sequences(57) RefSeq(19) UniProt(2)

Polymorphisms

SNPs within 2kb(741 from dbSNP Build 137)

Protein-related information

Resource	ID	Description
InterPro	IPR024880	COPII coat assembly protein, Sec16
InterPro	IPR024340	Sec16, central conserved domain
Protein Ontology	PR:000014582	protein transport protein Sec16B

References

(Earliest) J:71988 Misawa H, et al., Molecular cloning and sequencing of the cDNA coding for a novel regucalcin gene promoter region-related protein in rat, mouse and human liver. Int J Mol Med. 2001 Nov;8(5):513-20
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(29)