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Mageb4 Gene Detail
Summary
  • Symbol
    Mageb4
  • Name
    MAGE family member B4
  • Synonyms
    CN716893, Mage-b4, mMage-b4
Location &
Maps
more
  • Sequence Map
    ChrX:85293862-85299825 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 39.71 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    223 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2148568
 protein coding gene ChrX:85293860-85348699 (-)
129S1/SvImJ ENSMUSG00200031412
 protein coding gene ChrX:67306713-67361452 (-)
A/J ENSMUSG00195040719
 protein coding gene ChrX:71027981-71082713 (-)
AKR/J ENSMUSG00220027134
 protein coding gene ChrX:65915834-65970566 (-)
BALB/cJ ENSMUSG00180023804
 protein coding gene ChrX:67573497-67628221 (-)
C3H/HeJ ENSMUSG00175029984
 protein coding gene ChrX:71195442-71250168 (-)
C57BL/6NJ ENSMUSG00215013473
 protein coding gene ChrX:67722703-67777545 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033221
 protein coding gene ChrX:81315731-81317032 (-)
CAST/EiJ ENSTCUG00005037441
 protein coding gene ChrX:68781662-68841956 (-)
CBA/J ENSMUSG00210025368
 protein coding gene ChrX:67917759-67972490 (-)
DBA/2J ENSMUSG00185037352
 protein coding gene ChrX:80266632-80321371 (-)
FVB/NJ ENSMUSG00205018609
 protein coding gene ChrX:67207661-67262498 (-)
JF1/MsJ ENSUMUG00000021069
 protein coding gene ChrX:100996221-101057514 (-)
LP/J ENSMUSG00230010140
 protein coding gene ChrX:86913522-86968263 (-)
NOD/ShiLtJ ENSMUSG00190023906
 protein coding gene ChrX:67216680-67271515 (-)
NZO/HlLtJ ENSMUSG00225045156
 protein coding gene ChrX:92040152-92094982 (-)
PWK/PhJ ENSLUMG00010033049
 protein coding gene ChrX:66704842-66765676 (-)
SPRET/EiJ ENSMSPG00010022661
 protein coding gene ChrX:70436309-70506895 (-)
WSB/EiJ ENSIUOG00005042130
 protein coding gene ChrX:67810562-67865416 (-)



Homology
more
  • Human Ortholog
    MAGEB1, MAGE family member B1
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MAGEB1, MAGE family member B1
  • Synonyms
    CT3.1, DAM10, MAGEL1, MAGE-Xp
  • Links
    NCBI Gene ID: 4112
    UniProt: P43366

  • Chr Location
    Xp21.2; chrX:30243715-30252041 (+)  GRCh38
  • Human Ortholog
    MAGEB2, MAGE family member B2
  • Synonyms
    CT3.2, DAM6, MAGE-XP-2
  • Links
    NCBI Gene ID: 4113
    UniProt: O15479

  • Chr Location
    Xp21.2; chrX:30215563-30220089 (+)  GRCh38
  • Human Ortholog
    MAGEB4, MAGE family member B4
  • Synonyms
    CT3.6
  • Links
    NCBI Gene ID: 4115
    UniProt: O15481

  • Chr Location
    Xp21.2; chrX:30242000-30244187 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 1 genetic background
    4 phenotype references
Male mice homozygous for a null allele exhibit normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    734
  • Tissues
    68
  • cDNA Data
    10
  • Literature Summary
    13
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 434903 NCBI Gene Model | MGI Sequence Detail 5964 C57BL/6J ±  kb
    transcript NM_001033492 RefSeq | MGI Sequence Detail 2401 C57BL/6  
    polypeptide A2A9R3 UniProt | EBI | MGI Sequence Detail 556 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • InterPro Domains
      IPR002190 MAGE homology domain
      IPR041898 MAGE homology domain, winged helix WH1 motif
      IPR041899 MAGE homology domain, winged helix WH2 motif
      IPR037445 Melanoma-associated antigen
      IPR021072 Melanoma associated antigen, N-terminal
    Molecular
    Reagents
    less
    • All nucleic 18
      cDNA 11
      Primer pair 6
      Other 1
      Antibodies 2

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:3584456
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 13
      Gene Ontology 5
      Phenotypes 4
    • Earliest
      J:70948 Osterlund C, et al., Mage-b4, a novel melanoma antigen (MAGE) gene specifically expressed during germ cell differentiation. Cancer Res. 2000 Feb 15;60(4):1054-61
    • Latest
      J:338693 Li N, et al., MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice. Biochem Biophys Res Commun. 2023 Jul 10;675:46-53
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory