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Magee2 Gene Detail
Summary
  • Symbol
    Magee2
  • Name
    melanoma antigen, family E, 2
  • Synonyms
    9630059J11Rik, Mage-e2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2148316
    NCBI Gene: 272790
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:104854952-104857267 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 46.77 cM, cytoband C3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    21 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2148316
protein coding gene ChrX:104854952-104857267 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035993
protein coding gene ChrX:101595808-101598123 (-)
A/J MGP_AJ_G0035974
protein coding gene ChrX:101441852-101444157 (-)
AKR/J MGP_AKRJ_G0035892
protein coding gene ChrX:104597910-104600229 (-)
BALB/cJ MGP_BALBcJ_G0035964
protein coding gene ChrX:100251832-100254147 (-)
C3H/HeJ MGP_C3HHeJ_G0035670
protein coding gene ChrX:102046967-102049282 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036490
protein coding gene ChrX:104529987-104532302 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033318
protein coding gene ChrX:98995859-98998156 (-)
CAST/EiJ MGP_CASTEiJ_G0034956
protein coding gene ChrX:86261313-86263614 (-)
CBA/J MGP_CBAJ_G0035645
protein coding gene ChrX:107823613-107825928 (-)
DBA/2J MGP_DBA2J_G0035799
protein coding gene ChrX:100714157-100716476 (-)
FVB/NJ MGP_FVBNJ_G0035740
protein coding gene ChrX:100014543-100016858 (-)
LP/J MGP_LPJ_G0035892
protein coding gene ChrX:102565159-102567474 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035772
protein coding gene ChrX:112477335-112479650 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036516
protein coding gene ChrX:101258854-101261173 (-)
PWK/PhJ MGP_PWKPhJ_G0034654
protein coding gene ChrX:83800340-83802654 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034482
protein coding gene ChrX:86964819-86967128 (+)
WSB/EiJ MGP_WSBEiJ_G0035096
protein coding gene ChrX:99957144-99959463 (-)



Homology
more
  • Human Ortholog
    MAGEE2, MAGE family member E2
  • Vertebrate Orthologs
    7
  • Human Ortholog
    MAGEE2, MAGE family member E2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HCA3
  • Links
    NCBI Gene ID: 139599
    neXtProt AC: NX_Q8TD90
    UniProt: Q8TD90

  • Chr Location
    Xq13.3; chrX:75782988-75785244 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 272790 NCBI Gene Model | MGI Sequence Detail 2316 C57BL/6J ±  kb
transcript NM_053206 RefSeq | MGI Sequence Detail 2338 C57BL/6  
polypeptide NP_444436 RefSeq | MGI Sequence Detail 523 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR002190 MAGE homology domain
    IPR041898 MAGE homology domain, winged helix WH1 motif
    IPR041899 MAGE homology domain, winged helix WH2 motif
    IPR037445 Melanoma-associated antigen
Molecular
Reagents
less
  • All nucleic 12
    cDNA 11
    Primer pair 1

    Microarray probesets 1
Other
Accession IDs
less
MGI:2148037, MGI:3036244
References
more
  • Summaries
    All 30
    Developmental Gene Expression 8
    Phenotypes 3
  • Earliest
    J:70396 Chomez P, et al., An overview of the MAGE gene family with the identification of all human members of the family. Cancer Res. 2001 Jul 15;61(14):5544-51
  • Latest
    J:256265 Gordeeva OF, et al., Expression of Cancer-Testis Antigens of the Mage Family in Mouse Oocytes and Early Embryos. Russian Journal of Developmental Biology. 2017;48(4):287-294

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory