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Jade3
Gene Detail
Symbol

Name
ID
Jade3
jade family PHD finger 3
MGI:2148019
Synonyms
mKIAA0215, Phf16
Feature Type
protein coding gene
Genetic Map
Chromosome X
15.90 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
ChrX:20425688-20519939 bp, + strand
From VEGA annotation of GRCm38

  94252 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:40981  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: JADE3
Gene Tree: Jade3

Human
homologs
JADE3, jade family PHD finger 3
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 9767
neXtProt AC: NX_Q92613

Human Synonyms: JADE-3, PHF16

Human Chr (Location): Xp11.23; chrX:46912276-47061242 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Gene trapped(10) Targeted(2)
 
Male chimeras hemizygous for a gene trapped allele appear normal at E9.5.
 
Phenotype Images(10)
Interactions
Jade3 interacts with 338 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process histone H3 acetylation, histone H4-K12 acetylation, ...
Component histone acetyltransferase complex
Function metal ion binding, zinc ion binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (118)    Tissues (109)    Images (6)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 118
cDNA source data(34)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase jade3 ; ZFIN jade3    NEW 
Molecular
reagents
All nucleic(35) cDNA(34) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000017083 (Evidence)
Ensembl Gene Model ENSMUSG00000037315 (Evidence)
Entrez Gene 382207 (Evidence)
UniGene 281517
DFCI TC1612932, TC1597704, TC1626891
DoTS DT.101259689, DT.94251822, DT.101161451
NIA Mouse Gene Index U043749
Consensus CDS Project CCDS30042.1
International Mouse Phenotyping Consortium Status Jade3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017083 VEGA Gene Model | MGI Sequence Detail 94252 C57BL/6J ±  kb
transcript OTTMUST00000041366 VEGA | MGI Sequence Detail 4866 Not Applicable 
polypeptide OTTMUSP00000018564 VEGA | MGI Sequence Detail 824 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(8) UniProt(1)
Polymorphisms
SNPs within 2kb(104 from dbSNP Build 137)    SNPs within 2kb including multiple locations(108)
Protein-related
information
ResourceIDDescription
InterPro IPR019542 Enhancer of polycomb-like, N-terminal
InterPro IPR011011 Zinc finger, FYVE/PHD-type
InterPro IPR019787 Zinc finger, PHD-finger
InterPro IPR001965 Zinc finger, PHD-type
InterPro IPR019786 Zinc finger, PHD-type, conserved site
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
Protein Ontology PR:000012643 protein Jade-3
References
(Earliest) J:86562 Tzouanacou E, et al., Identification of Jade1, a gene encoding a PHD zinc finger protein, in a gene trap mutagenesis screen for genes involved in anteroposterior axis development. Mol Cell Biol. 2003 Dec;23(23):8553-2
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(34)
Other
accession IDs
MGI:2147927

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory