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Jade3 Gene Detail
Summary
  • Symbol
    Jade3
  • Name
    jade family PHD finger 3
  • Synonyms
    mKIAA0215, Phf16
  • Feature Type
    protein coding gene
  • IDs
    MGI:2148019
    NCBI Gene: 382207
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:20291927-20386178 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome X, 15.90 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    102 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2148019
protein coding gene ChrX:20291611-20386178 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035590
protein coding gene ChrX:15306899-15410545 (+)
A/J MGP_AJ_G0035567
protein coding gene ChrX:15405907-15500179 (+)
AKR/J MGP_AKRJ_G0035500
protein coding gene ChrX:15914264-16012494 (+)
BALB/cJ MGP_BALBcJ_G0035560
protein coding gene ChrX:15155853-15253136 (+)
C3H/HeJ MGP_C3HHeJ_G0035278
protein coding gene ChrX:15507081-15621945 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036096
protein coding gene ChrX:15713282-15810796 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032960
protein coding gene ChrX:13655526-13743699 (+)
CAST/EiJ MGP_CASTEiJ_G0034569
protein coding gene ChrX:14833028-14922233 (+)
CBA/J MGP_CBAJ_G0035247
protein coding gene ChrX:16432089-16539992 (+)
DBA/2J MGP_DBA2J_G0035399
protein coding gene ChrX:15205428-15301834 (+)
FVB/NJ MGP_FVBNJ_G0035345
protein coding gene ChrX:15111621-15203217 (+)
LP/J MGP_LPJ_G0035481
protein coding gene ChrX:15540411-15637844 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035389
protein coding gene ChrX:16692727-16796114 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036103
protein coding gene ChrX:15224688-15326832 (+)
PWK/PhJ MGP_PWKPhJ_G0034270
protein coding gene ChrX:14403111-14492460 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034110
protein coding gene ChrX:15202990-15301527 (+)
WSB/EiJ MGP_WSBEiJ_G0034704
protein coding gene ChrX:15101578-15194227 (+)



Homology
more
  • Human Ortholog
    JADE3, jade family PHD finger 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    JADE3, jade family PHD finger 3
  • Synonyms
    JADE-3, PHF16
  • Links
    NCBI Gene ID: 9767
    neXtProt AC: NX_Q92613
    UniProt: Q92613

  • Chr Location
    Xp11.3; chrX:46912276-47061242 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 images
    9 phenotype references
Male chimeras hemizygous for a gene trapped allele appear normal at E9.5.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037315 Ensembl Gene Model | MGI Sequence Detail 94252 C57BL/6J ±  kb
transcript ENSMUST00000115384 Ensembl | MGI Sequence Detail 4866 Not Applicable  
polypeptide ENSMUSP00000111042 Ensembl | MGI Sequence Detail 823 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
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  • All nucleic 36
    cDNA 35
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2147927
References
more
  • Summaries
    All 34
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:86562 Tzouanacou E, et al., Identification of Jade1, a gene encoding a PHD zinc finger protein, in a gene trap mutagenesis screen for genes involved in anteroposterior axis development. Mol Cell Biol. 2003 Dec;23(23):8553-2
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory