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AW112010 Gene Detail
Summary
  • Symbol
    AW112010
  • Name
    expressed sequence AW112010
  • Feature Type
    lncRNA gene
  • IDs
    MGI:2147706
    NCBI Gene: 107350
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:11047612-11050566 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 7.59 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    33 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2147706
 lncRNA gene Chr19:11047612-11055808 (-)
129S1/SvImJ MGP_129S1SvImJ_G0005814
 lincRNA gene Chr19:8428358-8432637 (-)
A/J MGP_AJ_G0005804
 lincRNA gene Chr19:7867110-7870461 (-)
AKR/J MGP_AKRJ_G0005780
 lincRNA gene Chr19:8164460-8167255 (-)
BALB/cJ MGP_BALBcJ_G0005783
 lincRNA gene Chr19:7905717-7908795 (-)
C3H/HeJ MGP_C3HHeJ_G0005731
 lincRNA gene Chr19:8057813-8060564 (-)
C57BL/6NJ MGP_C57BL6NJ_G0005943
 lincRNA gene Chr19:8804787-8809446 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0005285
 lincRNA gene Chr19:8299043-8301993 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0005717
 lincRNA gene Chr19:8860566-8863513 (-)
DBA/2J MGP_DBA2J_G0005736
 lincRNA gene Chr19:7865019-7868060 (-)
FVB/NJ MGP_FVBNJ_G0005763
 lincRNA gene Chr19:7913693-7916480 (-)
LP/J MGP_LPJ_G0005817
 lincRNA gene Chr19:8386473-8389419 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0005749
 lincRNA gene Chr19:8736734-8740852 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0005941
 lincRNA gene Chr19:8192904-8195694 (-)
PWK/PhJ MGP_PWKPhJ_G0005616
 lincRNA gene Chr19:7321920-7324967 (-)
SPRET/EiJ MGP_SPRETEiJ_G0005532
 lincRNA gene Chr19:7375828-7379739 (-)
WSB/EiJ MGP_WSBEiJ_G0005723
 lincRNA gene Chr19:8076892-8080161 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit increased susceptibility to S. Typhimurium infection, decreased susceptibility to DSS-induced colitis, and a defect in interleukin-12b and interleukin-6 production in response to LPS treatment.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    631
  • cDNA Data
    64
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 107350 NCBI Gene Model | MGI Sequence Detail 2955 C57BL/6J ±  kb
    transcript NR_102366 RefSeq | MGI Sequence Detail 790 C57BL/6  
    polypeptide Q3U6J0 UniProt | EBI | MGI Sequence Detail 78 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    Molecular
    Reagents
    less
    • All nucleic 64
      cDNA 64

      Microarray probesets 3
    References
    more
    • Summaries
      All 21
      Phenotypes 5
    • Earliest
      J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
    • Latest
      J:292504 Su Z, et al., LncRNA AW112010 Promotes Mitochondrial Biogenesis and Hair Cell Survival: Implications for Age-Related Hearing Loss. Oxid Med Cell Longev. 2019;2019:6150148
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2020
    MGI 6.15     		The Jackson Laboratory