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Aldh3b2 Gene Detail
Summary
  • Symbol
    Aldh3b2
  • Name
    aldehyde dehydrogenase 3 family, member B2
  • Synonyms
    C130048D07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2147613
    NCBI Gene: 621603
  • Gene Overview
    MyGene.info: ALDH3B2
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:3972328-3981646 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 3.69 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    29 from dbSNP Build 142
  • Strain Annotations
    12
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2147613
protein coding gene Chr19:3972328-3981665 (+)
129S1/SvImJ no annotation
A/J MGP_AJ_G0024603
protein coding gene Chr19:750013-759016 (+)
AKR/J MGP_AKRJ_G0024574
protein coding gene Chr19:776841-790510 (+)
BALB/cJ MGP_BALBcJ_G0024601
protein coding gene Chr19:760585-771709 (+)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0025049
protein coding gene Chr19:797757-808993 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022478
protein coding gene Chr19:715307-724646 (+)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0024340
protein coding gene Chr19:874686-886582 (+)
DBA/2J no annotation
FVB/NJ no annotation
LP/J MGP_LPJ_G0024555
protein coding gene Chr19:781550-795382 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024466
protein coding gene Chr19:826715-844557 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025097
protein coding gene Chr19:768834-778921 (+)
PWK/PhJ MGP_PWKPhJ_G0023588
protein coding gene Chr19:766098-775622 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023389
protein coding gene Chr19:665760-667973 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    ALDH3B2, aldehyde dehydrogenase 3 family member B2
  • Vertebrate Orthologs
    2
  • Human Ortholog
    ALDH3B2, aldehyde dehydrogenase 3 family member B2
    Orthology source: HGNC
  • Synonyms
    ALDH8
  • Links
    NCBI Gene ID: 222
    UniProt: P48448

  • Chr Location
    11q13.2; chr11:67662162-67681214 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000075296 Ensembl Gene Model | MGI Sequence Detail 9319 C57BL/6J ±  kb
transcript ENSMUST00000143380 Ensembl | MGI Sequence Detail 2142 Not Applicable  
polypeptide ENSMUSP00000115356 Ensembl | MGI Sequence Detail 479 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • EC
  • InterPro Domains
    IPR016163 Aldehyde dehydrogenase, C-terminal
    IPR016160 Aldehyde dehydrogenase, cysteine active site
    IPR015590 Aldehyde dehydrogenase domain
    IPR029510 Aldehyde dehydrogenase, glutamic acid active site
    IPR012394 Aldehyde dehydrogenase NAD(P)-dependent
    IPR016162 Aldehyde dehydrogenase, N-terminal
    IPR016161 Aldehyde/histidinol dehydrogenase
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 3
References
more
  • Summaries
    All 23
    Developmental Gene Expression 3
    Gene Ontology 4
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:218413 Kitamura T, et al., Mouse aldehyde dehydrogenase ALDH3B2 is localized to lipid droplets via two C-terminal tryptophan residues and lipid modification. Biochem J. 2015 Jan 1;465(1):79-87

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory