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Spindoc Gene Detail
Summary
  • Symbol
    Spindoc
  • Name
    spindlin interactor and repressor of chromatin binding
  • Synonyms
    AI846148
  • Feature Type
    protein coding gene
  • IDs
    MGI:2147611
    NCBI Gene: 68229
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:7356464-7383026 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 5.32 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    52 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2147611
protein coding gene Chr19:7356463-7383051 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024790
protein coding gene Chr19:4484724-4514579 (-)
A/J MGP_AJ_G0024757
protein coding gene Chr19:4130413-4157313 (-)
AKR/J MGP_AKRJ_G0024730
protein coding gene Chr19:4262677-4290856 (-)
BALB/cJ MGP_BALBcJ_G0024757
protein coding gene Chr19:4245933-4272973 (-)
C3H/HeJ MGP_C3HHeJ_G0024524
protein coding gene Chr19:4393674-4422938 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025203
protein coding gene Chr19:4573303-4603184 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022637
protein coding gene Chr19:4039381-4067080 (-)
CAST/EiJ MGP_CASTEiJ_G0023997
protein coding gene Chr19:4296989-4328443 (-)
CBA/J MGP_CBAJ_G0024497
protein coding gene Chr19:4652408-4683198 (-)
DBA/2J MGP_DBA2J_G0024624
protein coding gene Chr19:4096475-4123553 (-)
FVB/NJ MGP_FVBNJ_G0024589
protein coding gene Chr19:4137791-4164708 (-)
LP/J MGP_LPJ_G0024710
protein coding gene Chr19:4333643-4363143 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024619
protein coding gene Chr19:4547342-4575284 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025251
protein coding gene Chr19:4414877-4444860 (-)
PWK/PhJ MGP_PWKPhJ_G0023743
protein coding gene Chr19:4149972-4177148 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023547
protein coding gene Chr19:4217538-4243300 (-)
WSB/EiJ MGP_WSBEiJ_G0024059
protein coding gene Chr19:4313245-4340942 (-)



Homology
more
  • Human Ortholog
    SPINDOC, spindlin interactor and repressor of chromatin binding
  • Vertebrate Orthologs
    7
  • Human Ortholog
    SPINDOC, spindlin interactor and repressor of chromatin binding
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C11orf84, SPIN-DOC
  • Links
    NCBI Gene ID: 144097
    neXtProt AC: NX_Q9BUA3
    UniProt: Q9BUA3

  • Chr Location
    11q13.1; chr11:63813374-63827718 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024970 Ensembl Gene Model | MGI Sequence Detail 26563 C57BL/6J ±  kb
transcript ENSMUST00000025924 Ensembl | MGI Sequence Detail 3183 Not Applicable  
polypeptide ENSMUSP00000025924 Ensembl | MGI Sequence Detail 381 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 8
    Genomic 1
    cDNA 7

    Microarray probesets 5
References
more
  • Summaries
    All 23
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
  • Latest
    J:248451 Bae N, et al., A transcriptional coregulator, SPIN.DOC, attenuates the coactivator activity of Spindlin1. J Biol Chem. 2017 Dec 22;292(51):20808-20817

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/09/2019
MGI 6.13
The Jackson Laboratory