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Nmrk1 Gene Detail
Summary
  • Symbol
    Nmrk1
  • Name
    nicotinamide riboside kinase 1
  • Synonyms
    BC016495, D630020N23Rik, MGC:25909
  • Feature Type
    protein coding gene
  • IDs
    MGI:2147434
    NCBI Gene: 225994
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:18632016-18652428 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 13.17 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    239 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2147434
protein coding gene Chr19:18631950-18652428 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024967
protein coding gene Chr19:16506169-16526666 (+)
A/J MGP_AJ_G0024944
protein coding gene Chr19:15580704-15600948 (+)
AKR/J MGP_AKRJ_G0024914
protein coding gene Chr19:16199825-16220046 (+)
BALB/cJ MGP_BALBcJ_G0024943
protein coding gene Chr19:15611396-15631681 (+)
C3H/HeJ MGP_C3HHeJ_G0024701
protein coding gene Chr19:16137734-16158558 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025385
protein coding gene Chr19:17092365-17113980 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022804
protein coding gene Chr19:15952154-15973089 (+)
CAST/EiJ MGP_CASTEiJ_G0024169
protein coding gene Chr19:15779287-15799499 (+)
CBA/J MGP_CBAJ_G0024679
protein coding gene Chr19:17711954-17742952 (+)
DBA/2J MGP_DBA2J_G0024811
protein coding gene Chr19:15608558-15629559 (+)
FVB/NJ MGP_FVBNJ_G0024772
protein coding gene Chr19:15526973-15547401 (+)
LP/J MGP_LPJ_G0024895
protein coding gene Chr19:16479706-16500225 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024799
protein coding gene Chr19:17591127-17613218 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025440
protein coding gene Chr19:16132566-16153953 (+)
PWK/PhJ MGP_PWKPhJ_G0023918
protein coding gene Chr19:15148304-15169832 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023723
protein coding gene Chr19:15419250-15440753 (+)
WSB/EiJ MGP_WSBEiJ_G0024237
protein coding gene Chr19:16182469-16202909 (+)



Homology
more
  • Human Ortholog
    NMRK1, nicotinamide riboside kinase 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NMRK1, nicotinamide riboside kinase 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    bA235O14.2, C9orf95, NRK1
  • Links
    NCBI Gene ID: 54981
    neXtProt AC: NX_Q9NWW6
    UniProt: Q9NWW6

  • Chr Location
    9q21.13; chr9:75060577-75088319 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 6787
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: NMRK1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 225994 NCBI Gene Model | MGI Sequence Detail 20413 C57BL/6J ±  kb
transcript NM_145497 RefSeq | MGI Sequence Detail 1637 C57BL/6  
polypeptide Q91W63 UniProt | EBI | MGI Sequence Detail 195 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    cDNA 22

    Microarray probesets 5
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:242603 Ratajczak J, et al., NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells. Nat Commun. 2016 Oct 11;7:13103

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory