About   Help   FAQ
Slc6a7 Gene Detail
Summary
  • Symbol
    Slc6a7
  • Name
    solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
  • Synonyms
    MGC:61029, MGC:67444, Prot
  • Feature Type
    protein coding gene
  • IDs
    MGI:2147363
    NCBI Gene: 240332
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:60995376-61014199 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 34.41 cM, cytoband E1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    156 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2147363
protein coding gene Chr18:60995376-61014222 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024472
protein coding gene Chr18:60850376-60869220 (-)
A/J MGP_AJ_G0024439
protein coding gene Chr18:58241223-58260433 (-)
AKR/J MGP_AKRJ_G0024409
protein coding gene Chr18:59847677-59866545 (-)
BALB/cJ MGP_BALBcJ_G0024438
protein coding gene Chr18:58365951-58386509 (-)
C3H/HeJ MGP_C3HHeJ_G0024206
protein coding gene Chr18:60073727-60092546 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024885
protein coding gene Chr18:62504421-62523230 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022316
protein coding gene Chr18:57783868-57802965 (-)
CAST/EiJ MGP_CASTEiJ_G0023679
protein coding gene Chr18:59943009-59963751 (-)
CBA/J MGP_CBAJ_G0024176
protein coding gene Chr18:64512722-64531649 (-)
DBA/2J MGP_DBA2J_G0024306
protein coding gene Chr18:57911265-57930069 (-)
FVB/NJ MGP_FVBNJ_G0024272
protein coding gene Chr18:57319376-57338199 (-)
LP/J MGP_LPJ_G0024389
protein coding gene Chr18:60698177-60717043 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024301
protein coding gene Chr18:66139151-66159344 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024932
protein coding gene Chr18:60039657-60060108 (-)
PWK/PhJ MGP_PWKPhJ_G0023422
protein coding gene Chr18:58137547-58157017 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023228
protein coding gene Chr18:60267690-60286701 (-)
WSB/EiJ MGP_WSBEiJ_G0023743
protein coding gene Chr18:59894929-59913765 (-)



Homology
more
  • Human Ortholog
    SLC6A7, solute carrier family 6 member 7
  • Vertebrate Orthologs
    8
  • Human Ortholog
    SLC6A7, solute carrier family 6 member 7
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PROT
  • Links
    NCBI Gene ID: 6534
    neXtProt AC: NX_Q99884
    UniProt: Q99884

  • Chr Location
    5q32; chr5:150189861-150211072 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 240332 NCBI Gene Model | MGI Sequence Detail 18824 C57BL/6J ±  kb
transcript NM_201353 RefSeq | MGI Sequence Detail 3362 C57BL/6  
polypeptide Q6PGE7 UniProt | EBI | MGI Sequence Detail 637 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 11
    Primer pair 2

    Microarray probesets 1
References
more
  • Summaries
    All 29
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:241102 Leone DP, et al., Compensatory Actions of Ldb Adaptor Proteins During Corticospinal Motor Neuron Differentiation. Cereb Cortex. 2017 Feb 01;27(2):1686-1699

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/15/2019
MGI 6.14
The Jackson Laboratory