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Slc6a7 Gene Detail
Summary
  • Symbol
    Slc6a7
  • Name
    solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
  • Synonyms
    MGC:61029, MGC:67444, Prot
  • Feature Type
    protein coding gene
  • IDs
    MGI:2147363
    NCBI Gene: 240332
Location & Maps
more
  • Sequence Map
    Chr18:60995381-61014199 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      18819 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 34.41 cM, cytoband E1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SLC6A7, solute carrier family 6 member 7
  • Vertebrate Orthologs
    8
  • Human Ortholog
    SLC6A7, solute carrier family 6 member 7
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PROT
  • Links
    NCBI Gene ID: 6534
    neXtProt AC: NX_Q99884

  • Chr Location
    5q32; chr5:150189957-150211072 (+)  GRCh38.p2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    44
  • Tissues
    17
  • cDNA Data
    10
  • Literature Summary
    4
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000052026 Ensembl Gene Model | MGI Sequence Detail 18819 C57BL/6J ±  kb
transcript ENSMUST00000025520 Ensembl | MGI Sequence Detail 3342 Not Applicable  
polypeptide ENSMUSP00000025520 Ensembl | MGI Sequence Detail 637 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    156 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000015191 sodium-dependent proline transporter
  • InterPro Domains
    IPR000175 Sodium:neurotransmitter symporter
Molecular
Reagents
less
  • All nucleic 12
    cDNA 10
    Primer pair 2

    Microarray probesets 1
References
more
  • Summaries
    All 26
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:229226 Amaniti EM, et al., Expansion of the piriform cortex contributes to corticothalamic pathfinding defects in Gli3 conditional mutants. Cereb Cortex. 2015 Feb;25(2):460-71
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/20/2016
MGI 6.05 		The Jackson Laboratory